Department of Obstetrics and Gynaecology, The Aga Khan University, Karachi, Pakistan.
East Mediterr Health J. 2010 Mar;16(3):308-12.
This retrospective review of hospital records analysed pregnancy outcome with 2 different treatments for women with recurrent miscarriage diagnosed with antiphospholipid syndrome in the index pregnancy. Of 64 women, 29 had received aspirin and 35 aspirin plus heparin. Pregnancy-induced hypertension, prematurity, intrauterine growth restriction and neonatal death were considered as maternal and fetal complications. There were no significant differences in antenatal and maternal complications between the groups. HOwever, there were significant differences in mean anticardiolipin IgG antibody levels. Aspirin alone or in combination with parin was equally efficacious in women with antiphospholipid syndrome and recurrent miscarriage.
本回顾性医院病历研究分析了两种不同疗法对复发性流产合并抗磷脂抗体综合征孕妇的妊娠结局。64 名患者中，29 名接受阿司匹林治疗，35 名接受阿司匹林联合肝素治疗。妊娠高血压、早产、宫内生长受限和新生儿死亡被视为母婴并发症。两组间产前和母亲并发症无显著差异。然而，抗心磷脂 IgG 抗体水平存在显著差异。抗磷脂抗体综合征合并复发性流产患者单独使用阿司匹林或联合肝素治疗均有效。
