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B族链球菌感染所致新生儿暴发性紫癜

Neonatal purpura fulminans secondary to group B streptococcal infection.

作者信息

Zenciroglu Aysegul, Karagol Belma Saygili, Ipek Mehmet Sah, Okumus Nurullah, Yarali Nese, Aydin Mustafa

机构信息

Division of Neonatology, Sami Ulus Maternity, Childrens' Education and Research Hospital, Ankara, Turkey.

出版信息

Pediatr Hematol Oncol. 2010 Nov;27(8):620-5. doi: 10.3109/08880018.2010.503339.

Abstract

Purpura fulminans is an acute and frequently fatal disorder characterized by sudden onset of progressive cutaneous hemorrhage and necrosis due to dermal vascular thrombosis and disseminated intravascular coagulation. The authors present a neonate with extensive purpura fulminans due to group B streptoccoccal septicemia and evaluated the attributable clinical mortality and morbidity of this potentially lethal syndrome. Clinicians especially neonatologists should be aware that early-onset sepsis of group B Streptococcus in the newborn infant with purpura fulminans could be a cause of maternal carriage due to colonization of this pathogen microorganism.

摘要

暴发性紫癜是一种急性且常致命的疾病,其特征为因真皮血管血栓形成和弥散性血管内凝血导致的进行性皮肤出血和坏死的突然发作。作者报告了一名因B族链球菌败血症而患有广泛暴发性紫癜的新生儿,并评估了这种潜在致命综合征的临床死亡率和发病率。临床医生尤其是新生儿科医生应意识到,患有暴发性紫癜的新生儿早发性B族链球菌败血症可能是由于这种病原微生物定植导致的母体携带所致。

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