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遗传学与儿童肥胖:与护理实践的相关性。

Introduction to genetics and childhood obesity: relevance to nursing practice.

机构信息

University of North Dakota, 430 Oxford Street, Grand Forks, ND 58202, USA.

出版信息

Biol Res Nurs. 2011 Jan;13(1):61-9. doi: 10.1177/1099800410381424. Epub 2010 Aug 26.

Abstract

PURPOSE

The aims for this article are to provide an overview of the current state of research on genetic contributions to the development of childhood obesity and to suggest genetic-focused nursing practices to prevent childhood obesity.

ORGANIZING CONSTRUCTS

Genetic epidemiology of childhood obesity, modes to identifying obesity genes, types of human obesity genes, and nursing implications are discussed.

CLINICAL RELEVANCE

The successful integration of genetics into nursing practice will provide opportunities for nurses to participate fully as major agents and collaborators in the health care revolution.

CONCLUSIONS

Practicing nurses across the profession will need to become knowledgeable about genetics and take part in obesity prevention through genetic assessment of susceptibility and appropriate environmental interventions.

摘要

目的

本文旨在概述遗传因素在儿童肥胖症发展中的研究现状,并提出以遗传为重点的护理实践建议,以预防儿童肥胖症。

组织结构

讨论了儿童肥胖症的遗传流行病学、识别肥胖基因的方法、人类肥胖基因的类型以及护理意义。

临床相关性

将遗传学成功地融入护理实践将为护士提供充分参与医疗保健革命的机会,成为主要的推动者和合作者。

结论

整个护理行业的执业护士都需要了解遗传学知识,并通过对易感性的遗传评估和适当的环境干预来参与肥胖预防。

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本文引用的文献

1
Polygenic obesity in humans.人类多基因肥胖症。
Obes Facts. 2008;1(1):35-42. doi: 10.1159/000113935. Epub 2008 Feb 8.
3
Consequences of childhood obesity.儿童肥胖的后果。
Ann Acad Med Singap. 2009 Jan;38(1):75-7.
4
Missing heritability and GWAS utility.缺失的遗传力与全基因组关联研究的效用。
Obesity (Silver Spring). 2009 Feb;17(2):209-10. doi: 10.1038/oby.2008.613.
5
Gene-environment interaction and obesity.基因-环境相互作用与肥胖
Nutr Rev. 2008 Dec;66(12):684-94. doi: 10.1111/j.1753-4887.2008.00128.x.
6
FTO: the first gene contributing to common forms of human obesity.FTO:首个导致人类常见肥胖类型的基因。
Obes Rev. 2008 May;9(3):246-50. doi: 10.1111/j.1467-789X.2008.00481.x. Epub 2008 Mar 26.
8
Genetic epidemiology of obesity.肥胖的遗传流行病学
Epidemiol Rev. 2007;29:49-61. doi: 10.1093/epirev/mxm004. Epub 2007 Jun 12.

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