Institute for Occupational and Social Medicine, RWTH Aachen University, Aachen, Germany.
J Occup Environ Med. 2010 Sep;52(9):887-92. doi: 10.1097/JOM.0b013e3181f09077.
In this study, the effect of short-term exposure to welding fumes emitted by different welding techniques on workers was investigated.
In a 3-fold crossover study, six welders used three different welding techniques for 3 hours. Before and after welding, blood and urine samples were collected to perform biomonitoring of metals. Breath condensate was collected to assess inflammatory reactions, and lung function measurements were performed.
Welding led to a significant increase of chromium and nickel in blood and urine and of nitrate and nitrite in exhaled breath condensate. These increases were higher for manual metal arc welding with alloyed material (MAW-a). Several lung function parameters decreased after welding. This decrease was significantly higher after MAW-a.
In respect to biological effects, MAW-a seems to be more important than other welding techniques.
本研究旨在探讨短期接触不同焊接技术产生的焊接烟尘对工人的影响。
采用三交叉研究设计，六名焊工使用三种不同的焊接技术各 3 小时。在焊接前后采集血样和尿样进行金属生物监测，采集呼出气冷凝物评估炎症反应，并进行肺功能测量。
焊接导致血铬和血镍、尿铬和尿镍以及呼出气冷凝物中亚硝酸盐和硝酸盐显著增加。使用合金材料的手工金属电弧焊（MAW-a）引起的增加更为显著。焊接后几个肺功能参数下降，MAW-a 后下降更为显著。
就生物学效应而言，MAW-a 似乎比其他焊接技术更为重要。
