Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, South Korea.
Int J Cardiovasc Imaging. 2010 Dec;26(Suppl 2):213-21. doi: 10.1007/s10554-010-9692-2. Epub 2010 Aug 27.
To evaluate the agreement between dual-source computed tomography (DSCT) and two-dimensional transthoracic echocardiography (2D-TTE) with respect to the assessment of global left ventricular (LV) function in patients with severe arrhythmia. With 2D-TTE serving as the reference method, we performed both DSCT and 2D-TTE, at an interval of less than 2 days, in 54 patients with severe arrhythmia (average heart rate difference >30 beats per min) before open heart surgery for evaluation of valvular heart disease (VHD) and coronary artery disease. DSCT was performed using retrospective electrocardiography (ECG) without dose modulation. Ten phases of the cardiac cycle were analyzed for identification of end-diastolic and end-systolic phases with ECG-editing. Pearson's correlation coefficient (r) and Bland-Altman analysis were used to determine agreement for parameters of LV global function. Correlation between DSCT and 2D-TTE measurements was good or excellent in terms of the values of the LV ejection fraction (51.0 ± 11.4% vs. 55.8 ± 11.6%; r = 0.8), LV end-diastolic volume (179.5 ± 98.6 ml vs. 152.1 ± 73.8 ml; r = 0.95), LV end-systolic volume (90.7 ± 60.7 ml vs. 69.1 ± 46.8 ml; r = 0.90), and LV stroke volume (89.0 ± 48.1 ml vs. 82.9 ± 37.3 ml; r = 0.89). Left ventricular ejection fraction measured using DSCT was less than that measured using 2D-TTE by an average of -4.8 ± 7.3%. Dual-source CT with ECG editing can provide results comparable to those of 2D-TTE for assessment of LV global function in patients with severe arrhythmia.
评估双源 CT（DSCT）与二维经胸超声心动图（2D-TTE）在评估严重心律失常患者整体左心室（LV）功能方面的一致性。以 2D-TTE 为参考方法，我们对 54 例在心脏直视手术前因瓣膜性心脏病（VHD）和冠状动脉疾病而出现严重心律失常（平均心率差异>30 次/分钟）的患者进行了 DSCT 和 2D-TTE 检查，两次检查间隔时间少于 2 天。DSCT 使用回顾性心电图（ECG）进行，无需剂量调节。使用 ECG 编辑分析 10 个心动周期相位以识别舒张末期和收缩末期。使用 Pearson 相关系数（r）和 Bland-Altman 分析确定 LV 整体功能参数的一致性。DSCT 与 2D-TTE 测量值之间的相关性在 LV 射血分数（51.0±11.4% vs. 55.8±11.6%；r=0.8）、LV 舒张末期容积（179.5±98.6ml vs. 152.1±73.8ml；r=0.95）、LV 收缩末期容积（90.7±60.7ml vs. 69.1±46.8ml；r=0.90）和 LV 每搏量（89.0±48.1ml vs. 82.9±37.3ml；r=0.89）方面均为良好或优秀。使用 DSCT 测量的 LV 射血分数平均比使用 2D-TTE 测量的低 4.8±7.3%。带 ECG 编辑的双源 CT 可提供与 2D-TTE 相当的结果，用于评估严重心律失常患者的 LV 整体功能。
