Liu Hai-Bin, Fan Jing-Ping, Lin Shun-Zhang, Zhao Shu-Wei, Lin Zheng
Department of Otolaryngology-Head & Neck Surgery, ChangZheng Hospital, Second Military Medical University, Fengyang Road 415, Huangpu District, Shanghai, China.
Clin Neurol Neurosurg. 2011 Jan;113(1):57-8. doi: 10.1016/j.clineuro.2010.07.022. Epub 2010 Aug 25.
To explore the feasibility of using botulinum toxin type A (BTXA) to treat tinnitus due to stapedius myoclonus.
A piece of gelfoam containing BTXA (25 U/ml) was placed, through a perforation in tympanic membrane, into the middle ear cavity of a patient suffering from tinnitus due to stapedius myoclonus.
The tinnitus disappeared on the second day after the BTXA treatment. The patient was free of symptoms during a 3-month follow-up period. Tinnitus reappeared at 4 months, and disappeared after second BTXA local treatment.
Local BTXA treatment may be considered as a treatment for tinnitus caused by stapedius myoclonus.