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经腭部注射肉毒杆菌毒素治疗小儿中耳肌阵挛性客观性耳鸣:一例报告

Treatment of objective tinnitus with transpalatal Botox injection in a pediatric patient with middle ear myoclonus: A case report.

作者信息

Dang Jennifer, Carol Liu Yi-Chun

机构信息

Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.

Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2019 Jan;116:22-24. doi: 10.1016/j.ijporl.2018.09.024. Epub 2018 Sep 25.

Abstract

We describe a case of bilateral middle ear myoclonus (MEM) that was treated with trans-palatal Botox injection after failing surgery to section the tensor tympani and stapedial tendons. MEM is a rare disorder resulting from rhythmic contraction of middle ear muscles. An 8-year old girl presented with audible clicking tinnitus, and resultant inability to focus in school. Her parents declined medical therapy, and she underwent surgeries for tendon lysis, with only temporary relief. She had successful response to trans-palatal Botox injection to the tensor veli palatini aponeurosis. Trans-palatal Botox injection is a safe and reasonable alternative for treatment of MEM.

摘要

我们描述了一例双侧中耳肌阵挛(MEM)病例,该患者在切断鼓膜张肌和镫骨肌腱的手术失败后,接受了经腭部肉毒杆菌毒素注射治疗。MEM是一种由中耳肌肉节律性收缩引起的罕见疾病。一名8岁女孩出现可闻及的咔嗒声耳鸣,导致无法在学校集中注意力。她的父母拒绝药物治疗,她接受了肌腱松解手术,但仅获得了短暂缓解。她经腭部向腭帆张肌腱膜注射肉毒杆菌毒素后取得了成功。经腭部肉毒杆菌毒素注射是治疗MEM的一种安全且合理的替代方法。

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