Center for Human Reproduction (CHR)-New York and Foundation for Reproductive Medicine, NY, USA.
Reprod Biomed Online. 2010 Oct;21(4):440-3. doi: 10.1016/j.rbmo.2010.06.042. Epub 2010 Aug 26.
Medical care should be based on best available evidence. While randomized controlled trials (RCT) are currently considered a gold standard of study design, they are not always available and do not represent the only study format that can lead to best available evidence. This communication argues that overvaluation of RCT and undervaluation of other study formats in establishing best available evidence hurts progress in reproductive medicine and in medicine in general.
医疗保健应该基于最佳现有证据。虽然随机对照试验（RCT）目前被认为是研究设计的金标准，但它们并不总是可用的，也不代表唯一能产生最佳现有证据的研究形式。本通讯认为，在建立最佳现有证据方面，过度重视 RCT 和低估其他研究形式会阻碍生殖医学和一般医学的发展。
