Mattiasson-Robertson A, Twetman S
Department of Pedodontics, Faculty of Odontology, University of Gothenburg, Sweden.
Community Dent Oral Epidemiol. 1993 Dec;21(6):365-9. doi: 10.1111/j.1600-0528.1993.tb01100.x.
A salivary mutans streptococci test and past caries experience were used as predictors for caries increment in a 3-yr study comprising 655 12-yr-old schoolchildren from two areas with contrasting levels of fluoride in the drinking water. The mean caries (DMFS) increment was similar in both groups during the study period, but a significantly (P < 0.05) higher incidence of approximal enamel lesions was registered in children from the high fluoride area. In both groups, a statistically significant (P < 0.05-0.001) positive relationship between salivary mutans streptococci score and/or past caries experience at baseline on one hand and caries increment during the study period on the other was established. The past caries experience was the most powerful predictor of caries risk in both the low fluoride and the high fluoride area. The sum of the sensitivity and specificity was somewhat higher in the low fluoride area (138%) compared to the high fluoride area (123%). The salivary bacterial enumeration used alone or in combination with past caries experience as well as past approximal caries experience were less useful as predictors in both groups. The present findings indicate that the natural fluoride exposure has a limited influence on caries risk assessment and the caries predictive ability of the salivary bacterial test and past caries in populations with a low level of disease.
在一项为期3年的研究中，对来自两个饮用水氟含量不同地区的655名12岁学童进行了唾液变形链球菌检测和既往龋齿经历调查，以此作为龋齿增量的预测指标。在研究期间，两组的平均龋齿（DMFS）增量相似，但高氟地区儿童邻面釉质病变的发生率显著更高（P<0.05）。在两组中，均建立了基线时唾液变形链球菌评分和/或既往龋齿经历与研究期间龋齿增量之间具有统计学意义（P<0.05 - 0.001）的正相关关系。既往龋齿经历是低氟和高氟地区龋齿风险的最强预测指标。低氟地区的灵敏度和特异度之和（138%）略高于高氟地区（123%）。单独使用唾液细菌计数或与既往龋齿经历以及既往邻面龋齿经历相结合，在两组中作为预测指标的作用较小。目前的研究结果表明，在疾病水平较低的人群中，自然氟暴露对龋齿风险评估以及唾液细菌检测和既往龋齿的龋齿预测能力影响有限。
