Department of Neurology, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan.
Ultrasound Med Biol. 2010 Nov;36(11):1776-82. doi: 10.1016/j.ultrasmedbio.2010.07.006.
Cerebral venous outflow insufficiency via the internal jugular vein (IJV) is associated with several neurological disorders. However, a normal reference set of IJV hemodynamic parameters derived from a large, healthy population over a wide range of age has, until now, been lacking. Color-coded duplex sonography was performed on the IJVs of 349 subjects (55.60 ± 17.49,16 to 89 y; 167 M/182 F). With increasing age, increased lumen area and decreased time-averaged mean velocity of bilateral IJV and a decreased proportion of total flow volume, drainage in the left IJV were found. The frequency of left jugular venous reflux (JVR) also increased with aging. We report IJV hemodynamic parameters across a large population, which could be used as a normal reference for clinical and research purposes. Furthermore, we found a decreased proportion of venous drainage, increased JVR prevalence, dilated lumen and slowed flow velocity in the left IJV, all of which suggest increased left IJV outflow impedance with aging.
颈内静脉（IJV）的脑静脉流出不足与多种神经疾病有关。然而，到目前为止，还缺乏来自广泛年龄范围的大量健康人群的 IJV 血流动力学参数的正常参考值。对 349 名受试者的 IJVs 进行了彩色双功能超声检查（55.60±17.49，16 至 89 岁；167 名男性/182 名女性）。随着年龄的增长，双侧 IJV 的管腔面积增加，平均流速降低，总流量比例降低，左 IJV 的引流减少。左颈内静脉反流（JVR）的频率也随年龄增长而增加。我们报告了一个大人群的 IJV 血流动力学参数，这些参数可用于临床和研究目的的正常参考。此外，我们发现左 IJV 的静脉引流比例降低、JVR 发生率增加、管腔扩张和血流速度减慢，这表明随着年龄的增长，左 IJV 的流出阻抗增加。
