BC Centre for Excellence in HIV/AIDS, St Paul's Hospital, Vancouver, Canada.
Drug Alcohol Depend. 2011 Jan 15;113(2-3):172-6. doi: 10.1016/j.drugalcdep.2010.07.023. Epub 2010 Aug 30.
Vancouver, Canada has a pilot supervised injecting facility (SIF), where individuals can inject pre-obtained drugs under the supervision of medical staff. There has been concern that the program may facilitate ongoing drug use and delay entry into addiction treatment.
We used Cox regression to examine factors associated with the time to the cessation of injecting, for a minimum of 6 months, among a random sample of individuals recruited from within the Vancouver SIF. In further analyses, we evaluated the time to enrollment in addiction treatment.
Between December 2003 and June 2006, 1090 participants were recruited. In Cox regression, factors independently associated with drug use cessation included use of methadone maintenance therapy (Adjusted Hazard Ratio [AHR] = 1.57 [95% Confidence Interval [CI]: 1.02-2.40]) and other addiction treatment (AHR = 1.85 [95% CI: 1.06-3.24]). In subsequent analyses, factors independently associated with the initiation of addiction treatment included: regular SIF use at baseline (AHR = 1.33 [95% CI: 1.04-1.72]); having contact with the addiction counselor within the SIF (AHR = 1.54 [95% CI: 1.13-2.08]); and Aboriginal ancestry (AHR = 0.66 [95% CI: 0.47-0.92]).
While the role of addiction treatment in promoting injection cessation has been well described, these data indicate a potential role of SIF in promoting increased uptake of addiction treatment and subsequent injection cessation. The finding that Aboriginal persons were less likely to enroll in addiction treatment is consistent with prior reports and demonstrates the need for novel and culturally appropriate drug treatment approaches for this population.
加拿大温哥华设有一个有监督的注射设施(SIF)试点项目,在此,个人可以在医务人员的监督下注射事先获得的毒品。有人担心该项目可能会助长持续吸毒,并延迟进入戒毒治疗。
我们使用 Cox 回归分析,考察了在温哥华 SIF 内随机招募的个人中,与至少 6 个月内停止注射相关的因素。在进一步的分析中,我们评估了进入戒毒治疗的时间。
2003 年 12 月至 2006 年 6 月期间,共招募了 1090 名参与者。在 Cox 回归分析中,与停止吸毒独立相关的因素包括使用美沙酮维持治疗(调整后的危险比 [AHR] = 1.57 [95%置信区间 [CI]:1.02-2.40])和其他戒毒治疗(AHR = 1.85 [95% CI:1.06-3.24])。在随后的分析中,与开始戒毒治疗独立相关的因素包括:基线时定期使用 SIF(AHR = 1.33 [95% CI:1.04-1.72]);在 SIF 内与成瘾顾问接触(AHR = 1.54 [95% CI:1.13-2.08]);以及原住民血统(AHR = 0.66 [95% CI:0.47-0.92])。
虽然成瘾治疗在促进停止注射方面的作用已得到充分描述,但这些数据表明 SIF 可能在促进更多人接受成瘾治疗并随后停止注射方面发挥作用。原住民人群不太可能接受戒毒治疗的发现与之前的报告一致,表明需要针对该人群开发新的、文化上适宜的药物治疗方法。