Functional and Applied Biomechanics Laboratory, Rehabilitation Medicine Department, National Institutes of Health-Clinical Center, Bethesda, MD 20892, USA.
Parkinsonism Relat Disord. 2011 May;17(4):277-80. doi: 10.1016/j.parkreldis.2010.08.001. Epub 2010 Aug 30.
Gait and mobility problems are prominent features of Parkinson's Disease (PD), and are difficult to observe clinically in early stages of PD. We previously reported that gait changes were measurable in early to mid-stage PD subjects, when we used inertial sensors during an instrumented Timed Up and Go test (iTUG). With the advent of wearable inertial sensors, home assessment of mobility has become possible. We tested six people with early PD and eight control subjects using the iTUG in the home and laboratory. Our objectives were to 1) investigate the feasibility of testing subjects at home, and 2) compare performance at home versus laboratory. We found that home iTUG testing is feasible and the patients with PD were more affected than the healthy control subjects when tested at home.
步态和移动问题是帕金森病（PD）的突出特征，并且在 PD 的早期阶段难以在临床上观察到。我们之前报道过，当我们在仪器化计时起立和行走测试（iTUG）中使用惯性传感器时，早期到中期 PD 患者的步态变化是可测量的。随着可穿戴惯性传感器的出现，居家移动能力评估成为可能。我们在家中和实验室中使用 iTUG 测试了 6 名早期 PD 患者和 8 名对照受试者。我们的目的是 1）研究在家中测试受试者的可行性，以及 2）比较在家中和实验室中的表现。我们发现，在家中进行 iTUG 测试是可行的，与在实验室中测试相比，PD 患者在家中受到的影响更大。
