[Proliferation kinetics in rat urothelium after unilateral nephrectomy and various doses of dibutylnitrosamine application--an example of the roles of a one kidney state on carcinogenesis].

We investigated the proliferation of urothel of the rat after unilateral nephrectomy and application of DBN with drinking water in various doses. We controlled the measurement of proliferation with 3H-thymidine. The important results of our experiments with DBN-application and unilateral nephrectomy were: 1. the tumour-incidence is higher and 2. the tumour-appear is earlier than in experiments with only DBN.