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用于帕金森病的肾上腺髓质移植

Adrenal medullary transplantation for Parkinson's disease.

作者信息

Choi C R, Lee J S, Sung K W, Song J U

机构信息

Department of Neurosurgery, Catholic University Medical College, Seoul, Korea.

出版信息

Stereotact Funct Neurosurg. 1990;54-55:324-7. doi: 10.1159/000100229.

DOI:10.1159/000100229
PMID:2080348
Abstract

Autotransplantation of adrenal medullary tissue to the right caudate nucleus was performed in 8 patients (6 men and 2 women) with Parkinson's disease demonstrating mainly rigidity and bradykinesia. Their mean age was 52 years. The mean duration of Parkinson's disease was 7 years. Left adrenalectomy and open craniotomy were done to implant medullary tissue into the right caudate nucleus. The 6-month clinical findings were evaluated. 5 cases showed improvement, 2 cases remained unchanged and 1 was worse. There was no operative mortality, but 1 patient developed right frontal infarction postoperatively and 2 patients demonstrated subdural hygroma.

摘要

对8例主要表现为强直和运动迟缓的帕金森病患者(6例男性,2例女性)进行了肾上腺髓质组织自体移植至右侧尾状核的手术。他们的平均年龄为52岁。帕金森病的平均病程为7年。通过左肾上腺切除术和开颅手术将髓质组织植入右侧尾状核。对6个月时的临床结果进行了评估。5例显示有改善,2例无变化,1例病情恶化。无手术死亡,但1例患者术后发生右侧额叶梗死,2例患者出现硬膜下积液。

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Adrenal medullary transplantation for Parkinson's disease.用于帕金森病的肾上腺髓质移植
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Stereotactic transplantation of adrenal medullary tissue in Parkinson's disease.帕金森病中肾上腺髓质组织的立体定向移植
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