INSERM U646, Angers University, 10, rue André Boquel, France.
Chemistry. 2010 Oct 11;16(38):11516-29. doi: 10.1002/chem.201000808. Epub 2010 Aug 27.
In the field of nanometre-sized drug-delivery systems, a wide range of colloidal systems have been created in recent decades. All of the systems have a similar global structure, that is, an inner part and an external surface/interface. In several applications, the external interface is the support for desired properties and the basis of future developments. The engineering of the particle's surface is an emerging step in the design of systems at the nanometre scale. This review presents and summarises the available techniques with a particular attention to recent advances. It is also a base for future works in this expanding area of research.
在纳米药物输送系统领域，近几十年来已经开发出了广泛的胶体系统。所有这些系统都具有相似的整体结构，即内部和外部表面/界面。在一些应用中，外部界面是所需性能的支撑，也是未来发展的基础。粒子表面的工程是纳米尺度系统设计中的一个新兴步骤。本综述介绍并总结了现有的技术，特别关注了最近的进展。它也是该不断扩展的研究领域未来工作的基础。
