牛磺酸对日本女高中生健康的影响。

Taurine's health influence on Japanese high school girls.

机构信息

Super Science Course, Mukogawa Women's University Senior High School, Nishinomiya, 6638143, Japan.

出版信息

J Biomed Sci. 2010 Aug 24;17 Suppl 1(Suppl 1):S47. doi: 10.1186/1423-0127-17-S1-S47.

DOI:10.1186/1423-0127-17-S1-S47

PMID:20804624

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2994398/

Abstract

BACKGROUND

The prevalence of metabolic syndrome (MS) in children and adolescents has been increasing at an alarming rate. MS risks during childhood and adolescence adversely affect health conditions in later life. Thus, the characterization of their MS risks is a critical research field. The aims of this study are to survey the health status of Japanese adolescent females, a poorly characterized population, and to investigate the potential relationship between their MS risks and dietary factors like potassium (K) and taurine.

METHODS

Anthropometric characteristics of 243 healthy school girls aged 13 to 18 years were measured. Serum levels of triglycerides, total cholesterol and high-density lipoprotein (HDL), and plasma levels of glucose and insulin were analyzed in fasting blood samples. We assessed overweight, disturbed lipid prolife, higher blood pressure (hBP) and higher plasma glucose (hGlc) levels as indicators of MS risks. The relationships between MS risks and urinary K or taurine excretion were investigated by dividing into higher and lower groups at medians of their urinary excretions.

RESULTS

Half of junior high school (JHS) and one-quarter of senior high school (SHS) girls had at least one MS risk. The quite common risk was hGlc, the rates being 21% in JHS girls and 14% in SHS. The prevalence of being overweight and obesity were only small portions, the rate being 0% and 0% in JHS girls, and 10% and 1% in SHS, respectively. Substantial differences in the prevalence of hBP were observed between JHS (22%) and SHS (4%) girls. Furthermore, higher urinary K excretion group showed a significant decrease in triglyceride level (P = 0.03) and increase in HDL level (P = 0.003) compared with the lower. Also, the higher urinary taurine excretion group exhibited a significant reduction in triglyceride level (P = 0.04) compared with the lower.

CONCLUSIONS

These results indicate that control of plasma glucose level rather than body weight is a crucial task in Japanese pubertal girls, and that a dietary habit rich in K and taurine could improve their lipid profile. Nutritional education based on these findings would help to prevent the future development of MS in Japanese female adolescents.

摘要

背景

儿童和青少年代谢综合征（MS）的患病率呈惊人的速度上升。儿童和青少年时期的 MS 风险会对以后的健康状况产生不利影响。因此，对其 MS 风险的特征进行描述是一个至关重要的研究领域。本研究的目的是调查日本青春期少女的健康状况，这是一个特征描述较差的人群，并探讨其 MS 风险与钾（K）和牛磺酸等饮食因素之间的潜在关系。

方法

测量了 243 名 13 至 18 岁健康女学生的人体测量特征。在空腹血样中分析了血清甘油三酯、总胆固醇和高密度脂蛋白（HDL）以及血浆葡萄糖和胰岛素水平。我们将超重、脂质代谢紊乱、血压升高（hBP）和血糖升高（hGlc）水平评估为 MS 风险的指标。通过将尿液排泄中位数分为较高和较低两组，研究了 MS 风险与尿 K 或牛磺酸排泄之间的关系。

结果

一半的初中生（JHS）和四分之一的高中生（SHS）女孩至少有一种 MS 风险。相当常见的风险是 hGlc，初中生女孩的发生率为 21%，高中生为 14%。超重和肥胖的发生率仅占很小一部分，初中生女孩的发生率为 0%和 0%，高中生为 10%和 1%。初中生（22%）和高中生（4%）女孩的 hBP 患病率存在显著差异。此外，与低尿 K 排泄组相比，高尿 K 排泄组的甘油三酯水平显著降低（P = 0.03），HDL 水平显著升高（P = 0.003）。此外，与低尿牛磺酸排泄组相比，高尿牛磺酸排泄组的甘油三酯水平显著降低（P = 0.04）。