Geriatric Research Unit, Brain Sciences, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Menopause. 2011 Feb;18(2):129-32. doi: 10.1097/gme.0b013e3181ec58f8.
Menopausal hot flashes have been associated with increased scores on measures of anxiety. Anxiety measures are typically composed of items measuring somatic and affective symptoms. Because hot flash symptoms are similar to symptoms of somatic anxiety, we wanted to examine the differential contribution of somatic anxiety and affective anxiety to hot flash scores.
A total of 80 psychologically well-functioning postmenopausal women aged 50 to 64 years were administered the Zung Anxiety Index (ZAI), from which total score, somatic anxiety subscale score, and affective anxiety subscale score were calculated. The outcome measure was a hot flash score that incorporated both frequency and severity based on a 7-day diary. A linear regression analysis examined the association between hot flashes and the two anxiety subscales controlling for age, education, and sleep quality.
Higher score on somatic anxiety was significantly associated with higher hot flash score (P = 0.04), whereas the association with affective anxiety was not significant (P = 0.80). Higher total score on the ZAI was also significantly associated with higher hot flash score (P = 0.02).
These results suggest that the positive association between higher ZAI scores and hot flashes in recently postmenopausal women may be due to the overlap between the somatic manifestation of hot flashes and anxiety symptoms rather than to an affective anxiety disturbance. These results have potential implications for the care and treatment of postmenopausal women, but replication is required in other samples including women at different transition stages of menopause and women with psychiatric comorbidities.
绝经期潮热与焦虑评分升高有关。焦虑量表通常由测量躯体和情感症状的项目组成。由于潮热症状与躯体焦虑症状相似,我们希望研究躯体焦虑和情感焦虑对潮热评分的差异贡献。
共纳入 80 名心理状况良好的绝经后 50 至 64 岁女性,给予zung 焦虑量表(zai),计算总评分、躯体焦虑分量表评分和情感焦虑分量表评分。结局测量是基于 7 天日记的潮热评分,包括频率和严重程度。线性回归分析考察了在控制年龄、教育和睡眠质量的情况下,潮热与两个焦虑分量表之间的关联。
躯体焦虑评分越高,与潮热评分越高显著相关(p=0.04),而与情感焦虑的相关性不显著(p=0.80)。zai 的总分越高,与潮热评分越高也显著相关(p=0.02)。
这些结果表明,zai 评分较高与近期绝经后妇女潮热之间的正相关可能是由于潮热的躯体表现与焦虑症状之间的重叠,而不是情感焦虑障碍所致。这些结果对绝经后妇女的护理和治疗具有潜在意义,但需要在其他样本中进行复制,包括处于不同绝经过渡阶段的妇女和伴有精神共病的妇女。