University of Manchester, UK.
Br J Psychiatry. 2010 Sep;197(3):227-33. doi: 10.1192/bjp.bp.109.066845.
British Pakistani women have a high prevalence of depression. There are no reported psychosocial interventions for depression in ethnic minorities in the UK.
To determine the efficacy of a social group intervention compared with antidepressants, and whether the combination of the two is more efficacious than either alone.
A total of 123 women with depression participated in the primary care-based cluster randomised controlled trial (ISRCTN19172148). Outcome measures were severity of depression (Hamilton Rating Scale for Depression), social functioning and satisfaction at 3 and 9 months.
Greater improvement in depression in the social intervention group and the combined treatment group compared with those receiving antidepressants alone fell short of significance. There was significantly greater improvement in social functioning in the social intervention and combined treatment groups than in the antidepressant group at both 3 and 9 months.
Pakistani women with depression found the social groups acceptable and their social function and satisfaction improved if they received social treatment compared with the receipt of antidepressants alone.
英国裔巴基斯坦女性的抑郁症患病率很高。在英国,少数民族群体中没有针对抑郁症的报告的心理社会干预措施。
确定社会群体干预与抗抑郁药物相比的疗效,以及两者联合是否比单独使用任何一种更有效。
共有 123 名患有抑郁症的女性参与了这项基于初级保健的聚类随机对照试验(ISRCTN19172148)。主要结局测量为抑郁严重程度(汉密尔顿抑郁评定量表)、3 个月和 9 个月时的社会功能和满意度。
与单独接受抗抑郁药物治疗相比,社会干预组和联合治疗组的抑郁程度改善更大,但未达到显著水平。与仅接受抗抑郁药物治疗相比,社会干预组和联合治疗组在 3 个月和 9 个月时的社会功能改善更为显著。
患有抑郁症的巴基斯坦裔女性认为社会群体治疗是可以接受的,如果她们接受社会治疗而不是单独使用抗抑郁药物,她们的社会功能和满意度会有所提高。