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基层医疗中的结直肠癌筛查:将研究转化为实践。

Colorectal cancer screening in primary care: translating research into practice.

机构信息

Department of Family Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.

出版信息

Med Care. 2010 Oct;48(10):900-6. doi: 10.1097/MLR.0b013e3181ec5591.

Abstract

BACKGROUND

Colorectal cancer (CRC) screening is recommended for all adults 50 to 75 years old, yet only slightly more than one-half of eligible people are current with screening. Because CRC screening is usually initiated upon recommendations of primary care physicians, interventions in these settings are needed to improve screening.

OBJECTIVES

To assess the impact of a quality improvement intervention combining electronic medical record based audit and feedback, practice site visits for academic detailing and participatory planning, and "best-practice" dissemination on CRC screening in primary care practice.

RESEARCH DESIGN

Two-year group randomized trial.

SUBJECTS

Physicians, midlevel providers, and clinical staff members in 32 primary care practices in 19 States caring for 68,150 patients 50 years of age or older.

MEASURES

Proportion of active patients up-to-date (UTD) with CRC screening (colonoscopy within 10 years, sigmoidoscopy within 5 years, or at home fecal occult blood testing within 1 year) and having screening recommended within past year among those not UTD.

RESULTS

Patients 50 to 75 years in intervention practices exhibited significantly greater improvement (from 60.7% to 71.2%) in being UTD with CRC screening than patients in control practices (from 57.7% to 62.8%), the adjusted difference being 4.9% (95% confidence interval, 3.8%-6.1%). Recommendations for screening also increased more in intervention practices with the adjusted difference being 7.9% (95% confidence interval, 6.3%-9.5%). There was wide interpractice variation in CRC screening throughout the intervention.

CONCLUSIONS

A multicomponent quality improvement intervention in practices that use electronic medical record can improve CRC screening.

摘要

背景

结直肠癌(CRC)筛查建议适用于所有 50 至 75 岁的成年人,但只有略多于一半的符合条件的人正在接受筛查。由于 CRC 筛查通常是根据初级保健医生的建议进行的,因此需要在这些环境中进行干预以改善筛查。

目的

评估将电子病历为基础的审核和反馈、针对学术细化和参与式规划的实践现场访问以及“最佳实践”传播相结合的质量改进干预措施对初级保健实践中 CRC 筛查的影响。

研究设计

为期两年的群组随机试验。

受试者

19 个州的 32 个初级保健实践中的医生、中级提供者和临床工作人员,共照顾 68150 名 50 岁及以上的患者。

测量

未及时(UTD)进行 CRC 筛查(结肠镜检查 10 年内、乙状结肠镜检查 5 年内或家庭粪便潜血试验 1 年内)且过去一年内未建议进行筛查的活跃患者比例。

结果

干预实践中的 50 至 75 岁患者在 UTD 进行 CRC 筛查的比例(从 60.7%到 71.2%)明显高于对照组(从 57.7%到 62.8%),调整后的差异为 4.9%(95%置信区间,3.8%-6.1%)。筛查建议也在干预实践中增加了更多,调整后的差异为 7.9%(95%置信区间,6.3%-9.5%)。整个干预过程中,CRC 筛查的实践差异很大。

结论

在使用电子病历的实践中,多组分质量改进干预措施可以改善 CRC 筛查。

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