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腰椎手术后疑似海绵窦血栓形成与失明:一例罕见病例报告及文献综述

Suspected cavernous sinus thrombosis and blindness after lumbar spine surgery: A rare case report and literature review.

作者信息

Yuan Hao, Tian Yanjie, Li Xuemin

机构信息

Department of Ophthalmology, Peking University Third Hospital, No.49 Huayuan North Road, Haidian District, Beijing 100191, People's Republic of China; Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, No.49 Huayuan North Road, Haidian District, Beijing 100191, People's Republic of China.

Department of Ophthalmology, Peking University Third Hospital, No.49 Huayuan North Road, Haidian District, Beijing 100191, People's Republic of China; Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, No.49 Huayuan North Road, Haidian District, Beijing 100191, People's Republic of China.

出版信息

Int J Surg Case Rep. 2024 Sep;122:110183. doi: 10.1016/j.ijscr.2024.110183. Epub 2024 Aug 15.

Abstract

INTRODUCTION AND IMPORTANCE

Postoperative visual loss (POVL) is a relatively rare but devastating complication. We reported a case of POVL after spine surgery caused by ischemia of retina and optic nerve, and firstly introduced the possibility of cavernous sinus thrombosis in POVL development.

CASE PRESENTATION

A 67-year-old woman diagnosed with "lumbar spinal stenosis" was admitted to undergo posterior lumbar spinal canal decompression surgery because of the persistent lumbago and numbness. The operation was performed in the prone position under general anesthesia uneventfully. On the second day, the visual acuity of her right eye suddenly decreased to no light perception. The ophthalmic examination indicated edematous eyelid, chemosis, ptosis, ophthalmoplegia, relative afferent pupillary defect and higher orbital pressure in her affected eye, and funduscopic examination revealed pale optic disc, diffuse retinal welling and attenuated arteries. Cerebral magnetic resonance angiography implied the stenosis of cavernous sinus segment of right internal carotid artery. Aseptic cavernous sinus thrombosis and the secondary combined occlusion of central retinal and optic nerve vessels were suspected. Therefore, anticoagulation, vasodilation, oxygen and anti-inflammation treatment were timely administrated. One month after the treatment, swelling eyelid and ocular motion had markedly improved. However, there was no remarkable improvement in the patient's visual acuity.

CLINICAL DISCUSSION

Postoperative visual loss (POVL) after spine surgery is regarded as a serious complication with irreversible vision damage. It was alarming that cavernous sinus thrombosis might be a possible cause of POVL. High-volume fluid replacement, unstable hemodynamic parameters, prone position and prolonged surgical duration might bring about microvascular diseases and hypercoagulable state, contributing to the occurrence of POVL.

CONCLUSION

Our study firstly implied the possibility of cavernous sinus thrombosis in the POVL development. Detailed assessment, fluids management, hemodynamic stabilizing and duration optimization were proposed for POVL prevention.

摘要

引言与重要性

术后视力丧失(POVL)是一种相对罕见但极具破坏性的并发症。我们报告了一例脊柱手术后因视网膜和视神经缺血导致的POVL病例,并首次介绍了海绵窦血栓形成在POVL发生中的可能性。

病例介绍

一名67岁被诊断为“腰椎管狭窄症”的女性因持续腰痛和麻木入院接受后路腰椎管减压手术。手术在全身麻醉下俯卧位顺利进行。术后第二天,她右眼视力突然降至无光感。眼科检查显示患侧眼睑水肿、球结膜水肿、上睑下垂、眼球运动障碍、相对性传入瞳孔障碍及眶压升高,眼底检查发现视盘苍白、视网膜弥漫性水肿和动脉变细。脑部磁共振血管造影显示右侧颈内动脉海绵窦段狭窄。怀疑为无菌性海绵窦血栓形成及继发的视网膜中央和视神经血管联合阻塞。因此,及时给予抗凝、扩血管、吸氧及抗炎治疗。治疗一个月后,眼睑肿胀和眼球运动明显改善。然而,患者视力无明显改善。

临床讨论

脊柱手术后的术后视力丧失(POVL)被视为一种严重并发症,会导致不可逆的视力损害。令人担忧的是,海绵窦血栓形成可能是POVL的一个潜在原因。大量液体补充、不稳定的血流动力学参数、俯卧位和手术时间延长可能导致微血管疾病和高凝状态,从而促使POVL的发生。

结论

我们的研究首次提示了海绵窦血栓形成在POVL发生中的可能性。提出了针对POVL预防的详细评估、液体管理、血流动力学稳定及手术时间优化措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb3d/11378217/d57318c2c72d/gr1.jpg

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