Adler D, Aigner T, von Salis-Soglio G, Gutberlet M, Heyde C-E
Orthopädische Klinik und Poliklinik, Universität Leipzig, Liebigstrasse 20, 04103, Leipzig.
Orthopade. 2010 Nov;39(11):1065-70. doi: 10.1007/s00132-010-1648-7.
Nora's lesion, also known as "bizarre parosteal osteochondromatous proliferation" (BPOP), was first described in 1983 by the pathologist Nora. This lesion is defined as a proliferation of the bone. In most cases the lesion emanates from the intact cortical substance of short bones. It used to be assigned to reactive, heterotopic ossifications. More recent publications described constant genetic alterations supposing a tumorous genesis. Nora lesions are mostly found in the third or fourth decade of life; a preference of sexes is not described in the literature. They are characterized by a typical appearance in radiological diagnostics, but the diagnosis is ultimately determined by histopathological examination. Surgical resection is the therapy of choice.We report the case of a 29-year-old patient with an undetermined proliferation of the proximal ulna. The diagnosis of a Nora's lesion was made. The therapeutic approach, differential diagnosis and corresponding literature are presented and discussed.
诺拉氏病变，也称为“怪异的骨旁骨软骨瘤样增生”（BPOP），于1983年由病理学家诺拉首次描述。这种病变被定义为骨的增生。在大多数情况下，病变起源于短骨完整的皮质骨。它曾被归类为反应性异位骨化。最近的出版物描述了持续的基因改变，推测其为肿瘤性起源。诺拉氏病变多见于生命的第三个或第四个十年；文献中未描述性别偏好。它们在放射诊断中具有典型表现，但最终诊断由组织病理学检查确定。手术切除是首选治疗方法。我们报告了一例29岁近端尺骨未明确增生的患者。诊断为诺拉氏病变。并介绍和讨论了治疗方法、鉴别诊断及相关文献。
