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[跖骨奇异型骨旁骨软骨瘤样增生]

[Bizarre parosteal osteochondromatous proliferation of the metatarsal bone].

作者信息

Hartog C, Centmaier-Molnar V, Patzwahl R, Pfofe D, Wiewiorski M

机构信息

Klinik für Orthopädie und Traumatologie, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Schweiz.

Institut für Radiologie und Nuklearmedizin, Kantonsspital Winterthur, 8401, Winterthur, Schweiz.

出版信息

Orthopade. 2016 Oct;45(10):901-5. doi: 10.1007/s00132-016-3317-y.

Abstract

A bizarre parosteal osteochondromatous proliferation (BPOP), also known as a Nora lesion, is a rare benign bone formation. It emanates mainly from the intact cortex of the metaphysis of short tubular bones (hands or feet). Conventional radiographs should be complemented using cross-sectional imaging modalities (CT/MRI). In the absence of symptoms a non-operative regime with radiological and clinical controls is possible. If symptomatic, excision biopsy is the treatment of choice, though a high recurrence rate has been reported. Histopathological examination confirms the diagnosis and typically shows an endochondral ossification zone and an unusually mineralized cartilaginous matrix referred to as "blue bone".

摘要

一种奇特的骨旁骨软骨瘤样增生(BPOP),也被称为诺拉病变,是一种罕见的良性骨形成。它主要起源于短管状骨(手或足)干骺端的完整皮质。传统X线平片应辅以横断面成像方式(CT/MRI)。在无症状的情况下,可行非手术治疗并进行影像学和临床检查。如果出现症状,切除活检是首选治疗方法,不过有报道称复发率较高。组织病理学检查可确诊,通常显示软骨内成骨区和一种异常矿化的软骨基质,称为“蓝色骨”。

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