Hartog C, Centmaier-Molnar V, Patzwahl R, Pfofe D, Wiewiorski M
Klinik für Orthopädie und Traumatologie, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Schweiz.
Institut für Radiologie und Nuklearmedizin, Kantonsspital Winterthur, 8401, Winterthur, Schweiz.
Orthopade. 2016 Oct;45(10):901-5. doi: 10.1007/s00132-016-3317-y.
A bizarre parosteal osteochondromatous proliferation (BPOP), also known as a Nora lesion, is a rare benign bone formation. It emanates mainly from the intact cortex of the metaphysis of short tubular bones (hands or feet). Conventional radiographs should be complemented using cross-sectional imaging modalities (CT/MRI). In the absence of symptoms a non-operative regime with radiological and clinical controls is possible. If symptomatic, excision biopsy is the treatment of choice, though a high recurrence rate has been reported. Histopathological examination confirms the diagnosis and typically shows an endochondral ossification zone and an unusually mineralized cartilaginous matrix referred to as "blue bone".
一种奇特的骨旁骨软骨瘤样增生（BPOP），也被称为诺拉病变，是一种罕见的良性骨形成。它主要起源于短管状骨（手或足）干骺端的完整皮质。传统X线平片应辅以横断面成像方式（CT/MRI）。在无症状的情况下，可行非手术治疗并进行影像学和临床检查。如果出现症状，切除活检是首选治疗方法，不过有报道称复发率较高。组织病理学检查可确诊，通常显示软骨内成骨区和一种异常矿化的软骨基质，称为“蓝色骨”。
