Ortíz L J, Vázquez M, Sánchez J L
Department of Dermatology, University of Puerto Rico, School of Medicine, San Juan 00936-5067.
Bol Asoc Med P R. 1990 Oct;82(10):458-9.
Bullous pemphigoid has been reported in multiple publications to be associated with malignant neoplasms of different internal organ systems. This relationship was studied among forty patients seen at the Dermatology Clinics of the Puerto Rico Medical Center. The study demonstrated that Puerto Rican patients with bullous pemphigoid do not show an increased incidence of internal malignancy when compared with the general population matched for age, sex and study period. We conclude that extensive diagnostic studies for malignant neoplasms should not be the standard of care in patients with bullous pemphigoid. Additional studies should be guided by the clinical history and physical findings.
在多篇出版物中报道了大疱性类天疱疮与不同内部器官系统的恶性肿瘤有关。在波多黎各医学中心皮肤科诊所就诊的40例患者中对这种关系进行了研究。该研究表明，与年龄、性别和研究时期相匹配的普通人群相比，患有大疱性类天疱疮的波多黎各患者并未表现出内部恶性肿瘤发病率的增加。我们得出结论，对大疱性类天疱疮患者进行广泛的恶性肿瘤诊断性检查不应成为护理标准。应根据临床病史和体格检查结果指导进一步的研究。
