Hofschneider group, Leukocyte Migration, Max Planck Institute of Biochemistry, Martinsried, Germany.
EMBO J. 2010 Sep 1;29(17):2861-3. doi: 10.1038/emboj.2010.183.
Lymphocytes must undergo various modes of migration during an immune response, depending on the underlying substrate. The identification of a signalling module required specifically for 3D motility sheds light onto how these different migratory mechanisms can be regulated.
淋巴细胞在免疫应答过程中必须经历各种迁移方式,具体取决于潜在的基质。具体识别出一个信号模块对于 3D 运动是必需的,这揭示了如何调节这些不同的迁移机制。