Nyquist-Battie C
School of Basic Life Sciences, University of Missouri-Kansas City 64108.
Clin Exp Hypertens A. 1990;12(8):1453-72. doi: 10.3109/10641969009073530.
A regional study of acetylcholinesterase (AChE) molecular forms and choline acetyltransferase (ChAT) in the hearts of Dahl-salt sensitive (DS) and salt resistant (DR) rats was performed in animals administered either 8% or 0.35% dietary NaCl. Atria isolated from DS rats, regardless of dietary NaCl intake, had lower activities of all of the AChE molecular forms and ChAT when compared to their dietary-matched DR controls. In the ventricles, the activities of AChE molecular forms and ChAT were lower in DS rats compared to dietary-matched DR rats only when 8% NaCl diets were administered. The percent contribution of each of the molecular forms to the total AChE pool was not affected by animal strain or diet.
在给予8%或0.35%饮食NaCl的Dahl盐敏感（DS）和盐抵抗（DR）大鼠心脏中，进行了乙酰胆碱酯酶（AChE）分子形式和胆碱乙酰转移酶（ChAT）的区域研究。与饮食匹配的DR对照相比，无论饮食NaCl摄入量如何，从DS大鼠分离的心房中所有AChE分子形式和ChAT的活性均较低。在心室中，仅当给予8% NaCl饮食时，与饮食匹配的DR大鼠相比，DS大鼠中AChE分子形式和ChAT的活性较低。每种分子形式对总AChE池的贡献百分比不受动物品系或饮食的影响。
