Peterlin B Lee, Rosso Andrea L, Sheftell Fred D, Libon David J, Mossey Jana M, Merikangas Kathleen R
Johns Hopkins University, Bayview Medical Center, Baltimore, MD 21224, USA.
Cephalalgia. 2011 Jan;31(2):235-44. doi: 10.1177/0333102410378051. Epub 2010 Sep 2.
Post-traumatic stress disorder (PTSD) has been shown to be associated with migraine and drug abuse.
This was an analysis of data from the National Comorbidity Survey Replication (NCS-R) to evaluate the association of PTSD in those with episodic migraine (EM) and chronic daily headache (CDH).
Our sample consisted of 5,692 participants. Lifetime and 12-month prevalence rates of PTSD were increased in those with EM and CDH. After adjustments, the lifetime odds ratio (OR) of PTSD was greater in those with EM (OR 3.07 confidence interval [CI]: 2.12, 4.46) compared to those without headache; was greater in men than women with EM (men: OR 6.86; CI: 3.11, 15.11; women: OR 2.77; CI: 1.83, 4.21); and was comparable or greater than the association between migraine with depression or anxiety. The lifetime OR of PTSD was also increased in CDH sufferers. The OR of illicit drug abuse was not increased in those with EM or CDH unless co-occurring with PTSD or depression.
The lifetime and 12-month OR of PTSD is increased in those with migraine or CDH, and is greater in men than women with migraine. The lifetime and 12-month OR of illicit drug abuse is not increased in those with migraine or CDH unless co-occurring with PTSD or depression.
创伤后应激障碍（PTSD）已被证明与偏头痛和药物滥用有关。
这是一项对全国共病调查复制版（NCS-R）数据的分析，以评估发作性偏头痛（EM）和慢性每日头痛（CDH）患者中PTSD的相关性。
我们的样本包括5692名参与者。EM和CDH患者中PTSD的终生患病率和12个月患病率均有所增加。经过调整后，与无头痛者相比，EM患者中PTSD的终生优势比（OR）更高（OR 3.07，置信区间[CI]：2.12，4.46）；男性EM患者中的OR高于女性（男性：OR 6.86；CI：3.11，15.11；女性：OR 2.77；CI：1.83，4.21）；且与偏头痛与抑郁或焦虑之间的关联相当或更高。CDH患者中PTSD的终生OR也有所增加。EM或CDH患者中非法药物滥用的OR没有增加，除非同时伴有PTSD或抑郁。
偏头痛或CDH患者中PTSD的终生和12个月OR增加，且男性偏头痛患者中的OR高于女性。偏头痛或CDH患者中非法药物滥用的终生和12个月OR没有增加，除非同时伴有PTSD或抑郁。
