Mayo Clinic, Department of Radiology, Rochester, MN 55905, USA.
Magn Reson Imaging. 2010 Dec;28(10):1514-24. doi: 10.1016/j.mri.2010.06.016.
Magnetic resonance elastography (MRE) uses a phase-contrast MRI technique to image shear wave propagation in tissue followed by the mathematical inversion of the equations of motion governing tissue mechanics to noninvasively image tissue stiffness. This work investigates the impact of various MR sampling strategies designed to reduce acquisition times on the accuracy of MRE inversions. The results indicate that brain MRE data can be significantly truncated while maintaining a mean global stiffness error less than 10%. The results also indicate that brain MRE data can be collected in as few as eight lines of k-space. This degree of data truncation is possible due to the relatively low spatial frequency content and low amplitude of the shear waves observed during brain MRE exams and will facilitate the design of rapid brain MRE protocols for future clinical investigations.
磁共振弹性成像（MRE）使用相位对比 MRI 技术来成像组织中的剪切波传播，然后通过对控制组织力学的运动方程进行数学反演，非侵入性地成像组织的硬度。本研究探讨了各种旨在缩短采集时间的磁共振采样策略对 MRE 反演准确性的影响。结果表明，在保持平均全局硬度误差小于 10%的情况下，可以显著截断脑 MRE 数据。结果还表明，脑 MRE 数据可以在八个 k 空间线中收集。这种程度的数据截断是由于在脑 MRE 检查中观察到的剪切波的相对低空间频率内容和低幅度，这将有助于为未来的临床研究设计快速脑 MRE 方案。
