QuantiFERON-TB Gold 检测在筛查寻求庇护者中的结核病的预测价值。
Predictive values of QuantiFERON-TB Gold testing in screening for tuberculosis disease in asylum seekers.
机构信息
Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.
出版信息
Int J Tuberc Lung Dis. 2010 Sep;14(9):1209-11.
Screening with chest X-ray and the Mantoux test (the tuberculin skin test [TST]) is compulsory for adult asylum seekers who arrive in Norway. In 2005-2006, we included 823 asylum seekers in a study of the QuantiFERON-TB Gold test (QFT-G), and followed them for 23-32 months. Eight subjects with a positive and one with a negative QFT-G test were diagnosed with tuberculosis (TB). The positive (PPV) and negative predictive values (NPV) for TB were respectively 3.3% and 99.8%. The PPV was 2.3% and the NPV 99.1% for TST >or= 15 mm, and the NPV was 99.5% for TST >or= 6 mm in combination with a negative QFT-G.
对于抵达挪威的成年寻求庇护者，强制性地进行胸部 X 光和曼托试验（结核菌素皮肤试验[TST]）筛查。2005-2006 年，我们将 823 名寻求庇护者纳入 QuantiFERON-TB Gold 试验（QFT-G）研究中，并对他们进行了 23-32 个月的随访。8 名 QFT-G 检测阳性者和 1 名 QFT-G 检测阴性者被诊断为结核病（TB）。TB 的阳性预测值（PPV）和阴性预测值（NPV）分别为 3.3%和 99.8%。TST >or= 15 mm 时的 PPV 为 2.3%，NPV 为 99.1%，TST >or= 6 mm 且 QFT-G 阴性时的 NPV 为 99.5%。
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