Salinas Casado Jesús, Méndez Rubio Santiago, Campanario Pérez F, Virseda Chamorro Miguel, Martínez Urzay Germán, Pelaquim Humberto, Silmi Moyano Angel
Servicio de Urología, Hospital Clínico de San Carlos, Universidad Complutense de Madrid, Madrid, España.
Arch Esp Urol. 2010 Jul-Aug;63(6):441-53. doi: 10.4321/s0004-06142010000600005.
Our objective is to verify the diagnostic usefulness of ultrasound measurement of the thickness of the bladder wall, and the correlation with clinical/ urodynamic findings in patients with symptomatic BPH.
We performed a prospective cross-sectional study (cross-sectional study '') in a series of 74 males (age chi= 72.4 S = 7.1 (56-84 years) with symptomatic BPH. Patients completed the IPSS and determined the plasma level of PSAt (ng / ml). Before performing the urodynamic study, was determined by transabdominal ultrasonography (3.5 MHz transducer): prostate volume (cc) by the ellipsoid formula, and bladder wall thickness (mm) measured on the anterior bladder wall. Statistical analysis was performed using ANOVA, the Pearson correlation, and ROC curve.
It was a significant correlation of the sonographic thickness of the bladder wall with the IPSS (p = 0001, r = 0.38) (parameter in turn highly correlated with prostate volume and PSA (p = 0.01, r = 0.62)), as well as the detrusor hyperactivity (p = 0.03, r =0.21), cut off ROC curve: 3.85 mm. Instead, it was not shown a significant correlation between the sonographic thickness of the bladder wall and the urodynamic diagnosis of obstruction (Abrams and number Griffths p = 0223, r = 0.14) or the detrusor contractile power, measured in power at peak flow (Pw) (p = 0642 r =- 0.55), nor with age (p = 0303, r = 0.12). Neither correlation was observed with other non-invasive urodynamic measures (the maximum urinary flow flowmetry (p = 0318, r = 0.12) and percentage postmicturition residual (p = 0696, r = 0.05)).
The ultrasound measurement of bladder wall thickness, although it has not proved useful ness in our series in the diagnosis of the voiding phase (lower urinary tract obstruction and detrusor contractility impairment), on the contrary it can be introduced as a diagnostic technique for non-invasive studies in the alterations of the filling phase, in the form of detrusor hyperactivity in also patients with symptomatic BPH, and present a significant correlation with prostate growth.
我们的目的是验证超声测量膀胱壁厚度的诊断价值，以及其与有症状良性前列腺增生（BPH）患者临床/尿动力学检查结果的相关性。
我们对74例有症状BPH男性患者（年龄χ = 72.4，S = 7.1（56 - 84岁））进行了一项前瞻性横断面研究（横断面研究）。患者完成国际前列腺症状评分（IPSS）并测定血清前列腺特异抗原（PSA）水平（ng/ml）。在进行尿动力学检查前，通过经腹超声检查（3.5MHz探头）：采用椭圆体公式测定前列腺体积（cc），并在前壁膀胱壁测量膀胱壁厚度（mm）。采用方差分析、Pearson相关性分析和ROC曲线进行统计分析。
膀胱壁超声厚度与IPSS显著相关（p = 0.001，r = 0.38）（该参数又与前列腺体积和PSA高度相关（p = 0.01，r = 0.62）），以及与逼尿肌过度活动相关（p = 0.03，r = 0.21），ROC曲线截断值：3.85mm。相反，膀胱壁超声厚度与梗阻的尿动力学诊断（Abrams和Griffths数值，p = 0.223，r = 0.14）或在峰值尿流功率（Pw）下测量的逼尿肌收缩力之间未显示出显著相关性（p = 0.642，r = -0.55），与年龄也无相关性（p = 0.303，r = 0.12）。与其他非侵入性尿动力学指标（最大尿流率（p = 0.318，r = 0.12）和排尿后残余尿量百分比（p = 0.696，r = 0.05））均未观察到相关性。
膀胱壁厚度的超声测量，尽管在我们的系列研究中未证明对排尿期（下尿路梗阻和逼尿肌收缩功能损害）的诊断有用，但相反，它可作为一种诊断技术用于充盈期改变的非侵入性研究，表现为有症状BPH患者的逼尿肌过度活动，并且与前列腺增生显著相关。
