Obesity and Quality of Life Consulting, 762 Ninth Street #563, Durham, NC 27705, USA.
Obes Surg. 2011 Apr;21(4):457-64. doi: 10.1007/s11695-010-0261-5.
Health-related quality of life (HRQOL) is impaired in severely obese individuals presenting for bariatric surgery. Little is known about the relationship between cardiorespiratory fitness (CRF) and HRQOL in these individuals. We hypothesized that better HRQOL would be reported by those with higher CRF. In 326 gastric bypass patients (mean BMI = 46.5 ± 7.0; mean age=40.9 ± 10.1; 83.4% female), pre-surgical CRF was quantified as duration (minutes) of a submaximal treadmill test to 80% of age-predicted maximal heart rate (MHR). Patients completed both a general measure of HRQOL [the Medical Outcome Short Form 36 (SF-36)] and a weight-specific measure of HRQOL [Impact of Weight on Quality of Life--Lite]. Mean HRQOL scores were examined, controlling for age, gender, and BMI. Mean treadmill duration was 9.9 ± 3.1 min, and percent age-predicted MHR was 81.2 ± 3.0%. Higher cardiorespiratory fitness tended to be associated with better physical and weight-specific HRQOL. Adjustment for differences in gender, age, and BMI attenuated the significance of associations between fitness and physical measures from the SF-36, whereas adjustment eliminated significance of associations between fitness and weight-specific HRQOL in most cases. Results suggest that CRF confers some HRQOL benefits in severely obese adults, though these benefits may largely be explained by differences in age, gender, and BMI.
健康相关的生活质量（HRQOL）在接受减重手术的严重肥胖个体中受损。对于这些个体的心肺功能（CRF）与 HRQOL 之间的关系知之甚少。我们假设心肺功能更好的人报告的 HRQOL 会更好。在 326 名胃旁路手术患者中（平均 BMI=46.5±7.0；平均年龄=40.9±10.1；83.4%为女性），术前心肺功能通过 80%预测最大心率（MHR）的次最大跑步机测试持续时间（分钟）来量化。患者完成了一般 HRQOL 测量[医疗结局短期表 36（SF-36）]和体重特异性 HRQOL 测量[体重对生活质量的影响-精简版]。在控制年龄、性别和 BMI 的情况下，检查了平均 HRQOL 评分。平均跑步机持续时间为 9.9±3.1 分钟，预测 MHR 的百分比为 81.2±3.0%。较高的心肺功能与更好的身体和体重特异性 HRQOL 相关。调整性别、年龄和 BMI 的差异减弱了与 SF-36 中身体测量相关的体能与关联的显著性，而在大多数情况下，调整消除了与体重特异性 HRQOL 相关的体能与关联的显著性。结果表明，CRF 为严重肥胖成年人提供了一些 HRQOL 益处，尽管这些益处可能在很大程度上可以通过年龄、性别和 BMI 的差异来解释。
