铜催化的二或三甲氧基苯芳烃 C-H 键与二硫化物的硫醇化反应。
Copper-catalyzed thiolation of the di- or trimethoxybenzene arene C-H bond with disulfides.
机构信息
College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325027, People's Republic of China.
出版信息
J Org Chem. 2010 Oct 1;75(19):6732-5. doi: 10.1021/jo1014849.
PMID:20822119
Abstract
A CuI-catalyzed direct access to sulfides from disulfides via C-H bond cleavage of di- or trimethoxybenzene is described. The procedure utilizes O(2) as a clean and cheap oxidant. Direct selenation of the C-H bond also took place under this procedure. Furthermore, the system enables the use of two RS in (RS)(2). Thus, it represents an atom-economical procedure for the synthesis of sulfides and selenides.
摘要
本文描述了一种通过二或三甲氧基苯的 C-H 键断裂，从二硫化物中直接催化生成硫化物的方法。该反应以 O(2) 作为清洁、廉价的氧化剂。在这个过程中，C-H 键也可以直接硒化。此外，该体系还可以使两个 RS 在 (RS)(2) 中同时反应。因此，该方法代表了一种原子经济性的合成硫化物和硒化物的方法。
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