Neuropsychopharmacology and Brain Imaging and Heffter Research Center, University Hospital of Psychiatry Zurich, Zurich, Switzerland.
PLoS One. 2010 Aug 31;5(8):e12412. doi: 10.1371/journal.pone.0012412.
The OAV questionnaire has been developed to integrate research on altered states of consciousness (ASC). It measures three primary and one secondary dimensions of ASC that are hypothesized to be invariant across ASC induction methods. The OAV rating scale has been in use for more than 20 years and applied internationally in a broad range of research fields, yet its factorial structure has never been tested by structural equation modeling techniques and its psychometric properties have never been examined in large samples of experimentally induced ASC.
METHODOLOGY/PRINCIPAL FINDINGS: The present study conducted a psychometric evaluation of the OAV in a sample of psilocybin (n = 327), ketamine (n = 162), and MDMA (n = 102) induced ASC that was obtained by pooling data from 43 experimental studies. The factorial structure was examined by confirmatory factor analysis, exploratory structural equation modeling, hierarchical item clustering (ICLUST), and multiple indicators multiple causes (MIMIC) modeling. The originally proposed model did not fit the data well even if zero-constraints on non-target factor loadings and residual correlations were relaxed. Furthermore, ICLUST suggested that the "oceanic boundlessness" and "visionary restructuralization" factors could be combined on a high level of the construct hierarchy. However, because these factors were multidimensional, we extracted and examined 11 new lower order factors. MIMIC modeling indicated that these factors were highly measurement invariant across drugs, settings, questionnaire versions, and sexes. The new factors were also demonstrated to have improved homogeneities, satisfactory reliabilities, discriminant and convergent validities, and to differentiate well among the three drug groups.
CONCLUSIONS/SIGNIFICANCE: The original scales of the OAV were shown to be multidimensional constructs. Eleven new lower order scales were constructed and demonstrated to have desirable psychometric properties. The new lower order scales are most likely better suited to assess drug induced ASC.
OAV 问卷旨在整合对意识改变状态(ASC)的研究。它测量了三个主要维度和一个次要维度的 ASC,这些维度被假设在 ASC 诱导方法之间是不变的。OAV 评定量表已经使用了 20 多年,并在国际上广泛应用于多个研究领域,但它的因子结构从未通过结构方程模型技术进行过测试,其心理测量特性也从未在大量实验诱导 ASC 样本中进行过检验。
方法/主要发现:本研究通过对来自 43 项实验研究的数据进行汇总,在一组致幻蘑菇碱(n=327)、氯胺酮(n=162)和 MDMA(n=102)诱导 ASC 的样本中对 OAV 进行了心理测量评估。使用验证性因子分析、探索性结构方程建模、层次项目聚类(ICLUST)和多指标多原因(MIMIC)建模来检验因子结构。即使放松了对非目标因子负荷和残差相关性的零约束,最初提出的模型也不能很好地拟合数据。此外,ICLUST 表明,“海洋无边无际”和“幻觉重构”因素可以在建构层次的较高水平上结合。然而,由于这些因素是多维的,我们提取并检验了 11 个新的低阶因素。MIMIC 模型表明,这些因素在药物、环境、问卷版本和性别之间具有高度的测量不变性。新的因素还表现出更高的同质性、令人满意的可靠性、区分和收敛有效性,并且能够很好地区分三组药物。
结论/意义:OAV 的原始量表被证明是多维结构。构建了 11 个新的低阶量表,并证明具有良好的心理测量特性。新的低阶量表更适合评估药物诱导的 ASC。