Health Outcomes and Behavior Program, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, MRC-PSY, Tampa, FL 33612, USA.
Support Care Cancer. 2010 Feb;19(2):169-85. doi: 10.1007/s00520-010-0989-4. Epub 2010 Sep 8.
Fatigue is one of the most common symptoms experienced by persons with chronic illness, including cancer. The effective management of fatigue hinges in part on the accuracy and reliability of its measurement. The purpose of this study was to review and characterize the use of the 14-item Fatigue Symptom Inventory (FSI) in published studies and to evaluate the available evidence for its psychometric properties.
A systematic review of the literature identified 55 studies reporting results for the FSI. Data were analyzed to characterize internal consistency reliability of multi-item FSI scales and test-retest reliability. Correlation coefficients were summarized to characterize concurrent, convergent, and divergent validity. Standardized effect sizes were calculated to characterize the discriminative validity of the FSI and its sensitivity to change.
Sample sizes across studies ranged from 9-1,756. Approximately half of the samples consisted exclusively of females. Alpha coefficients for multi-item scales ranged from 0.84-0.96. Most items demonstrated low to moderate test-retest correlations. Correlations with other fatigue measures ranged from 0.41-0.86. Correlations with depression and anxiety measures were positive (range = 0.23-0.76). Correlations with measures of vitality and vigor were negative (range = -0.28 to -0.77). Effect sizes for discriminative validity and sensitivity to change ranged from small to medium and from small to large, respectively.
Findings provide good empirical evidence of the usefulness of the FSI and strongly support its use in future studies.
疲劳是患有慢性疾病（包括癌症）的人最常见的症状之一。疲劳的有效管理部分取决于其测量的准确性和可靠性。本研究的目的是回顾和描述已发表研究中使用 14 项疲劳症状量表（FSI）的情况，并评估其心理测量特性的现有证据。
通过系统文献回顾，确定了 55 项报告 FSI 结果的研究。对数据进行分析，以描述多项目 FSI 量表的内部一致性可靠性和重测信度。总结相关系数以描述同时性、收敛性和发散性有效性。计算标准化效应大小以描述 FSI 的判别有效性及其对变化的敏感性。
研究中的样本量范围为 9-1756。大约一半的样本仅由女性组成。多项目量表的α系数范围为 0.84-0.96。大多数项目的测试重测相关性较低至中等。与其他疲劳测量的相关性从 0.41 到 0.86。与抑郁和焦虑测量的相关性为正（范围为 0.23-0.76）。与活力和活力测量的相关性为负（范围为-0.28 至-0.77）。判别有效性和对变化的敏感性的效应大小分别从小到大，从小到大。
研究结果为 FSI 的有用性提供了良好的经验证据，并强烈支持其在未来研究中的应用。
