Kawachi Yasuhiro, Taguchi Shijima, Fujisawa Yasuhiro, Furuta Junichi, Nakamura Yasuhiro, Ishii Yoshiyuki, Otsuka Fujio
Department of Dermatology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.
Pediatr Dermatol. 2011 Mar-Apr;28(2):205-7. doi: 10.1111/j.1525-1470.2010.01249.x. Epub 2010 Sep 1.
The linear arrangement of discoid lupus erythematosus is uncommon. Here, we report a 6-year-old Japanese girl with linear discoid lupus erythematosus following the lines of Blaschko on her face and neck. Topical tacrolimus treatment improved the eruptions. The present case also indicated the important role of epidermal and dermal cells as well as immune cells in the pathogenesis of cutaneous lupus erythematodes.
盘状红斑狼疮的线状排列并不常见。在此，我们报告一名6岁日本女孩，其面部和颈部沿Blaschko线出现线状盘状红斑狼疮。外用他克莫司治疗使皮疹得到改善。本病例还表明了表皮和真皮细胞以及免疫细胞在皮肤红斑狼疮发病机制中的重要作用。
