Northeast Georgia Medical Center, Gainesville, USA.
Acta Paediatr. 2011 Feb;100(2):188-92. doi: 10.1111/j.1651-2227.2010.02001.x. Epub 2010 Oct 15.
To identify whether pulse oximetry technology is associated with decreased retinopathy of prematurity (ROP) and laser treatment.
Inborn infants <1250 g who had eye exams were compared at two centres in three periods. In Period 1, SpO₂ target was ≥93% and pulse oximetry technology was the same in both Centres. In Period 2, guidelines for SpO₂ 88-93% were implemented at both centres and Centre B changed to oximeters with signal extraction technology (SET(®)) while Centre A did not, but did so in Period 3. One ophthalmology department performed eye exams using international criteria.
In 571 newborns <1250 g, birth weight and gestational age were similar in the different periods and centres. At Centre A, severe ROP and need for laser remained the same in Periods 1 and 2, decreasing in Period 3-6% and 3%, respectively. At Centre B, severe ROP decreased from 12% (Period 1) to 5% (Period 2) and need for laser decreased from 5% to 3%, remaining low in Period 3.
In a large group of inborn infants <1250 g, a change in clinical practice in combination with pulse oximetry with Masimo SET, but not without it, led to significant reduction in severe ROP and need for laser therapy. Pulse oximetry selection is important in managing critically ill infants.
确定脉搏血氧饱和度技术是否与早产儿视网膜病变（ROP）和激光治疗减少有关。
在两个中心的三个时期比较了体重<1250 克的早产儿的眼部检查。在第 1 期，SpO₂ 目标值≥93%，两个中心的脉搏血氧饱和度技术相同。在第 2 期，两个中心都实施了 SpO₂ 88-93%的指南，中心 B 将脉搏血氧饱和度仪更换为具有信号提取技术（SET(®)）的仪器，而中心 A 没有，但在第 3 期进行了更换。一个眼科部门使用国际标准进行眼部检查。
在 571 名体重<1250 克的新生儿中，不同时期和中心的出生体重和胎龄相似。在中心 A，严重 ROP 和激光治疗的需求在第 1 期和第 2 期相同，在第 3 期分别减少了 6%和 3%。在中心 B，严重 ROP 从第 1 期的 12%下降到第 2 期的 5%，激光治疗的需求从第 5 期的 5%下降到第 3 期的 3%，在第 3 期保持较低水平。
在一大群体重<1250 克的早产儿中，临床实践的改变结合使用脉搏血氧饱和度 Masimo SET，而不是没有它，显著降低了严重 ROP 和激光治疗的需求。脉搏血氧饱和度的选择在管理危重症婴儿方面很重要。
