Sheffield Teaching Hospitals, Sheffield, UK.
Curr Opin Urol. 2010 Nov;20(6):453-8. doi: 10.1097/MOU.0b013e32833ee8d5.
To provide a review of the latest evidence on the management of anterior urethral strictures.
A continuing role exists for urethrotomy or dilatation in the management of urethral strictures as first-line therapy in selected patients. In those patients with bulbar strictures who fail or are not suitable for these procedures, an anastomotic urethroplasty, and if not feasible a substitution urethroplasty using either a flap or oral mucosal graft either by a dorsal, lateral or ventral onlay approach should be considered. For penile strictures, a ventral onlay procedure using skin can be considered except in cases of lichen sclerosis when an onlay procedure utilizing oral mucosa provides the best results using either a one-stage or two-stage approach.
Various options exist for the management of anterior urethral stricture disease. The 'reconstructive ladder' has served to guide urologists over the years. The selection of the correct procedure should be patient-centred and based on the latest evidence.
提供最新的关于前尿道狭窄治疗的证据综述。
尿道切开术或扩张术在某些患者中作为一线治疗方法,在尿道狭窄的管理中仍然具有重要作用。对于球部狭窄的患者,如果这些方法失败或不适用,应考虑吻合性尿道成形术,如果不可行,则应考虑使用皮瓣或口腔黏膜移植物的替代尿道成形术,通过背侧、外侧或腹侧覆盖法。对于阴茎狭窄,除了硬化性苔藓外,可以考虑使用腹侧覆盖法,使用皮肤,而在硬化性苔藓中,使用口腔黏膜的覆盖法可以提供最佳结果,无论是一期还是二期手术。
对于前尿道狭窄疾病的治疗有多种选择。“重建阶梯”多年来一直指导着泌尿科医生。选择正确的方法应该以患者为中心,并基于最新的证据。