Zhang Wei, Jiang Zhi-guo, Jiang Dao-zhen, Zheng Xiang-min, Shen Hong-liang, Shan Cheng-xiang, Liu Sheng, Qiu Ming
18F Minimally Invasive Surgical Center, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Clin Dev Immunol. 2010;2010:459143. doi: 10.1155/2010/459143. Epub 2010 Aug 17.
We evaluated the invasiveness of breast approach endoscopic thyroidectomy (BAET) carried out by surgeon very experienced in this procedure. Twenty-four patients who underwent BAET and 19 patients who underwent conventional thyroidectomy were the study population. Postoperative pain was assessed by a visual analog scale (VAS). The values 2, 12, and 24 h after surgery were significantly lower in the BAET group than those in the conventional group. Serum IL-6 and CRP levels were measured by an ELISA preoperatively and at 2, 12, 24 and 48 h after operation. Their values increased significantly after both procedures when compared to preoperative levels with significant differences between the two groups detected at the 24-hour and 48-hour time points. Subjective and objective evidence supported the notion that BAET could become a minimally invasive procedure if the surgeon gained sufficient experience.
我们评估了由在此手术方面经验丰富的外科医生实施的经乳晕入路内镜甲状腺切除术(BAET)的侵袭性。接受BAET的24例患者和接受传统甲状腺切除术的19例患者为研究对象。术后疼痛采用视觉模拟评分法(VAS)进行评估。BAET组术后2、12和24小时的值显著低于传统组。术前及术后2、12、24和48小时通过酶联免疫吸附测定法(ELISA)测量血清白细胞介素-6(IL-6)和C反应蛋白(CRP)水平。与术前水平相比,两种手术术后这些值均显著升高,在24小时和48小时时间点两组之间检测到显著差异。主观和客观证据支持这样一种观点,即如果外科医生获得足够的经验,BAET可以成为一种微创手术。