Department of Urology, Princess Al Johara Al Ibrahim Center for Cancer Research, King Saud University, Saudi Arabia.
Aging Male. 2011 Mar;14(1):33-6. doi: 10.3109/13685538.2010.512373. Epub 2010 Sep 9.
To develop and to validate an Arabic Aging Male Symptoms (AMS) tool and to clinically assess patients with hypogonadism after hormonal treatment.
The tool was translated into Arabic and tested on 15 Saudi men. During a period of 9 months all males presented to the andrology clinic of the main University Hospital, King Saud University, Saudi Arabia with signs and symptoms of hypogonadism, were included in the study. Arabic AMS scale was applied in the base line visit, then 12 weeks after treatment. Testosterone was monitored before treatment, 4 weeks and after 12 weeks.
Ninety-two subjects were included, Cronbach's α of 0.91 showed a very good internal consistency of the Arabic AMS questionnaire. The corresponding α for the subscales were 0.83, 0.84 and 0.73. There was a significant improvement in the mean level of TT after hormonal therapy (HT), this was reflected on the mean differences of improvement in the total Arabic AMS scores and subscales scores after HT, ranged from 31 to 35%.
The present study revealed a significant association between testosterone levels and AMS tool manifested by a its good ability to measure the effect of treatment on quality of life for patients with hypogonadism.
开发并验证阿拉伯男性衰老症状（AMS）工具，并在激素治疗后对性腺功能减退症患者进行临床评估。
该工具被翻译成阿拉伯语，并在 15 名沙特男性中进行了测试。在 9 个月的时间里，所有出现性腺功能减退症状和体征的男性都被纳入沙特阿拉伯国王大学主要医院男科诊所的研究中。在基线就诊时应用阿拉伯 AMS 量表，然后在治疗后 12 周进行评估。在治疗前、4 周和 12 周监测睾酮。
92 名受试者被纳入研究，阿拉伯 AMS 问卷的克朗巴赫 α 系数为 0.91，表明其内部一致性非常好。亚量表的相应 α 值分别为 0.83、0.84 和 0.73。激素治疗（HT）后 TT 平均水平显著提高，这反映在 HT 后总阿拉伯 AMS 评分和亚量表评分的平均改善差异上，范围为 31 至 35%。
本研究表明，睾酮水平与 AMS 工具之间存在显著关联，其能够很好地衡量治疗对性腺功能减退症患者生活质量的影响。
