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一名患有乳糜泻的13岁女孩在无麸质饮食3个月后出现肺含铁血黄素沉着症:病例报告及文献复习

Pulmonary haemosiderosis in a 13-year-old girl with coeliac disease after 3 months on a gluten-free diet: case report and review of the literature.

作者信息

Najada A S, Dahabreh M M

机构信息

Division of Pediatric Pulmonology, Queen Rania Al Abdullah Hospital for Children, Amman, Jordan.

出版信息

Ann Trop Paediatr. 2010;30(3):249-53. doi: 10.1179/146532810X12786388978841.

Abstract

A 13-year-old girl with controlled coeliac disease who had been on a gluten-free diet for the past 3 months was admitted with respiratory distress and hypoxia for the past week. Chest radiograph and CT scan showed bilateral widespread alveolar shadowing suggestive of a hypersensitive pneumonitis. There was a dramatic radiological and clinical response to oral corticosteroids. Bronchial lavage was suggestive of recurrent aspiration and histology of a transbronchial biopsy showed pulmonary haemosiderosis. We conclude that pulmonary haemosiderosis may occur in children with coeliac disease who are on a gluten-free diet.

摘要

一名13岁患有乳糜泻且病情得到控制的女孩,过去3个月一直遵循无麸质饮食,因过去一周出现呼吸窘迫和低氧血症入院。胸部X光片和CT扫描显示双侧广泛的肺泡阴影,提示过敏性肺炎。口服皮质类固醇后,影像学和临床症状出现显著改善。支气管灌洗提示反复误吸,经支气管活检的组织学检查显示为肺含铁血黄素沉着症。我们得出结论,患有乳糜泻且遵循无麸质饮食的儿童可能会发生肺含铁血黄素沉着症。

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