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与乳糜泻相关的肺含铁血黄素沉着症。

Pulmonary hemosiderosis in association with celiac disease.

作者信息

Hoca Nevin Taci, Dayioglu Didem, Ogretensoy Mihriban

机构信息

Department of Respiratory Medicine, Ataturk Chest Disease and Thoracic Surgery Eduation and Research Hospital, Ankara, Turkey.

出版信息

Lung. 2006 Sep-Oct;184(5):297-300. doi: 10.1007/s00408-005-2596-6.

Abstract

A 15-year-old male had a history of increasing dyspnea on exertion, cough, sputum production, fever, weakness, hemoptysis, and diarrhea. Chest radiography demonstrated bilateral alveolar consolidation. Bronchoalveolar lavage fluid analysis revealed extensive hemosiderin-laden alveolar macrophages. On the basis of iron deficiency anemia, diarrhea, raised antigliadin and antiendomysial antibodies, widespread villous atrophy, and crypt hyperplasia on intestinal biopsy, celiac disease was diagnosed. After treatment with a gluten-free diet, all his clinical symptoms and radiographic findings improved within two weeks.

摘要

一名15岁男性有劳力性呼吸困难加重、咳嗽、咳痰、发热、乏力、咯血及腹泻病史。胸部X线片显示双侧肺泡实变。支气管肺泡灌洗液分析显示大量含铁血黄素的肺泡巨噬细胞。基于缺铁性贫血、腹泻、抗麦胶蛋白及抗肌内膜抗体升高、广泛的绒毛萎缩以及肠道活检显示隐窝增生,诊断为乳糜泻。采用无麸质饮食治疗后,他所有的临床症状及影像学表现均在两周内改善。

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