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[在产气荚膜梭菌(魏氏梭菌)因子存在的情况下,大鼠胸腺和肝脏胸苷激酶参与的胸苷磷酸化作用]

[Thymidine phosphorylation with the participation of rat thymic and hepatic thymidine kinase in the presence of a factor from Cl. perfringens (welchii)].

作者信息

Siluianova S N, Eremenko V V

出版信息

Vopr Med Khim. 1978 Mar-Apr;24(2):184-8.

PMID:208287
Abstract

Factor CPW, isolated from Cl. perfringens/welchii was shown to activate latent thymidine kinase (factor N) from liver tissue of rats beginning from 42 days age. CPW factor activated 3.5-fold also thymidine kinase from rat strumous gland; the enzyme was observed during involution of the tissue. The data suggest that increase in thymidine kinase activity in proliferating tissues is related to activation of latent enzymes.

摘要

从产气荚膜梭菌/韦氏梭菌中分离出的CPW因子被证明能激活42日龄及以上大鼠肝脏组织中的潜在胸苷激酶(因子N)。CPW因子还能使大鼠甲状腺肿腺中的胸苷激酶活性提高3.5倍;该酶在组织退化过程中被观察到。数据表明,增殖组织中胸苷激酶活性的增加与潜在酶的激活有关。

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1
[Thymidine phosphorylation with the participation of rat thymic and hepatic thymidine kinase in the presence of a factor from Cl. perfringens (welchii)].[在产气荚膜梭菌(魏氏梭菌)因子存在的情况下,大鼠胸腺和肝脏胸苷激酶参与的胸苷磷酸化作用]
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Relative activities of thymidylate synthetase and thymidine kinase in rat tissues.大鼠组织中胸苷酸合成酶和胸苷激酶的相对活性。
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