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在非裔牙买加人中，脂联素水平和体脂分布的性别差异：纵向观察。

Sex-differences in adiponectin levels and body fat distribution: longitudinal observations in Afro-Jamaicans.

机构信息

Tropical Medicine Research Institute, University of the West Indies, Mona, Jamaica.

出版信息

Diabetes Res Clin Pract. 2010 Nov;90(2):e33-6. doi: 10.1016/j.diabres.2010.08.008. Epub 2010 Sep 15.

DOI:10.1016/j.diabres.2010.08.008
PMID:20828849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2953571/
Abstract

We longitudinally explored the relationship of body size and adiponectin levels in 393 community-dwelling Afro-Jamaicans. Adiponectin levels were greater in women, increased with age and declined with abdominal adiposity. Multivariate regression analyses suggest that subcutaneous fat in women may contribute significantly to the variance in their adiponectin levels.

摘要

我们在 393 名居住在社区的牙买加非裔人群中纵向研究了身体大小和脂联素水平之间的关系。脂联素水平在女性中更高，随年龄增长而增加，并随腹部肥胖而下降。多元回归分析表明，女性的皮下脂肪可能对其脂联素水平的差异有重要贡献。

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本文引用的文献

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J Clin Endocrinol Metab. 2009 Oct;94(10):4010-5. doi: 10.1210/jc.2009-0980. Epub 2009 Sep 15.
2
Visceral and subcutaneous adiposity and adiponectin in middle-aged Japanese men: the ERA JUMP study.日本中年男性的内脏及皮下脂肪与脂联素：ERA JUMP研究
Obesity (Silver Spring). 2009 Jun;17(6):1269-73. doi: 10.1038/oby.2009.3. Epub 2009 Feb 19.
3
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4
Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans.人体循环脂联素浓度的生理、药理及营养调节
Metab Syndr Relat Disord. 2008 Jun;6(2):87-102. doi: 10.1089/met.2007.0029.
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Hypertrophy and hyperplasia of abdominal adipose tissues in women.女性腹部脂肪组织的肥大与增生
Int J Obes (Lond). 2008 Feb;32(2):283-91. doi: 10.1038/sj.ijo.0803708. Epub 2007 Aug 28.
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Why might South Asians be so susceptible to central obesity and its atherogenic consequences? The adipose tissue overflow hypothesis.为什么南亚人如此容易患中心性肥胖及其致动脉粥样硬化后果？脂肪组织溢出假说。
Int J Epidemiol. 2007 Feb;36(1):220-5. doi: 10.1093/ije/dyl245.
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Eur J Endocrinol. 2005 Jul;153(1):91-8. doi: 10.1530/eje.1.01930.
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Adiponectin and adiponectin receptors.脂联素与脂联素受体。
Endocr Rev. 2005 May;26(3):439-51. doi: 10.1210/er.2005-0005.
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Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes.睾酮通过抑制脂联素从脂肪细胞的分泌，选择性地降低其高分子量形式。
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Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels.脂联素水平的性别差异在青春期发育过程中出现，并与血清雄激素水平相关。
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