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为感染艾滋病毒的儿童和感染艾滋病毒的成人提供口腔保健的差异:普通牙医指南

The differences between providing oral health care to HIV-infected children and HIV-infected adults: a general dentist's guide.

作者信息

Gonzales Cara B, Smith Stacey, Galvan Alicia, Mabry Jeffrey

机构信息

Department of Dental Diagnostic Science, University of Texas Health Science Center at San Antonio, USA.

出版信息

Gen Dent. 2010 Sep-Oct;58(5):424-32; quiz 733-4.

Abstract

People with HIV and AIDS are living much longer today, thanks to a better understanding of the disease process and the development of effective antiviral drugs and multidrug therapies. Consequently, HIV is now considered a chronic disease, one that affects nearly 40 million people worldwide. Highly active anti-retroviral therapy (HAART), first instituted in 1996, has led to a dramatic reduction in the number of perinatally infected children; however, in 2004, there were still 640,000 children under the age of 15 living with HIV worldwide.1 This population of patients faces more mature health issues compared to most children their age. For example, rampant dental decay is common among children with HIV and requires advanced treatment planning that needs to be closely coordinated with members of the medical team. Maintaining good oral health in combination with medication compliance leads to sustained overall health in HIV-infected children; however, many of the medications these children take have severe adverse effects on their oral health. Furthermore, these medications may interfere with other medications that are prescribed or administered in connection with oral health care. Lastly, the systemic and oral manifestations of HIV and AIDS are different for children than they are for adults; as a result, the prognosis and treatment options for these manifestations vary, depending on the patient's age. This article will address factors that affect the oral health of HIV-infected children and adults, as well as common oral manifestations of HIV and AIDS. Key differences in treatment planning for HIV-infected children and HIV-infected adults will be outlined.

摘要

如今,由于对疾病进程有了更深入的了解,以及有效抗病毒药物和多种药物疗法的发展,感染艾滋病毒和患艾滋病的人寿命延长了许多。因此,艾滋病毒现在被视为一种慢性病,全球近4000万人受其影响。1996年首次采用的高效抗逆转录病毒疗法(HAART),已使围产期感染儿童的数量大幅减少;然而,2004年,全球仍有64万15岁以下儿童感染艾滋病毒。与大多数同龄儿童相比,这群患者面临着更成熟的健康问题。例如,艾滋病毒感染儿童中猖獗的龋齿很常见,需要进行高级治疗规划,且需要与医疗团队成员密切协调。保持良好的口腔健康并配合药物治疗,可使感染艾滋病毒的儿童保持整体健康;然而,这些儿童服用的许多药物对其口腔健康有严重的不良影响。此外,这些药物可能会干扰与口腔保健相关的其他处方或施用的药物。最后,艾滋病毒和艾滋病在儿童中的全身和口腔表现与成人不同;因此,这些表现的预后和治疗选择因患者年龄而异。本文将探讨影响感染艾滋病毒的儿童和成人口腔健康的因素,以及艾滋病毒和艾滋病常见的口腔表现。还将概述感染艾滋病毒的儿童和成人在治疗规划上的关键差异。

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