Heinrich R, Hoffmann E, Holzhütter H G
Sektion Biologie, Bereich Biophysik, Humboldt-Universität Berlin, Germany.
Biomed Biochim Acta. 1990;49(8-9):891-902.
Optimal values of the rate constants of a reversible enzymatic reaction are calculated by maximizing the enzymatic activity. The results depend on the substrate and product concentrations. Expressions for optimal maximal activities are derived and conclusions are drawn for the optimal ratios of substrate concentrations and Michaelis-constants.
通过使酶活性最大化来计算可逆酶促反应速率常数的最佳值。结果取决于底物和产物浓度。推导了最佳最大活性的表达式，并得出了底物浓度与米氏常数的最佳比例的结论。
