Agharkar Research Institute, Pune, India.
Ophthalmic Res. 2010;44(3):166-72. doi: 10.1159/000316477. Epub 2010 Sep 9.
The lens is the ocular structure most susceptible to oxidative damage. Antioxidants, micronutrients and phytochemicals have been extensively studied for their possible effects to prevent or delay the progression of various eye diseases.
A brief overview of the updated literature on the role of antioxidants and micronutrients in the prevention and treatment of ocular diseases is to be presented with an emphasis on cataract.
PubMed search and individual papers from journals.
The review discusses linkages of various micronutrients and antioxidants as well as oxidative stress with cataract. Dietary interventions as strategy for prevention of cataract and other ocular disorders are also reviewed.
Consumption of food-based antioxidants like β-carotene lutein and zeaxanthin seem to be useful for the treatment of macular degeneration and cataracts. Supplements of vitamin A, vitamin C, vitamin E and zinc may prevent advanced age-related macular degeneration only in high-risk individuals.
晶状体是最易受到氧化损伤的眼部结构。抗氧化剂、微量营养素和植物化学物质已被广泛研究，以探讨其预防或延缓各种眼部疾病进展的可能性。
简要概述抗氧化剂和微量营养素在预防和治疗眼部疾病中的作用的最新文献，重点介绍白内障。
PubMed 搜索和期刊上的个别论文。
本综述讨论了各种微量营养素和抗氧化剂以及氧化应激与白内障的关系。还回顾了饮食干预作为预防白内障和其他眼部疾病的策略。
食用β-胡萝卜素、叶黄素和玉米黄质等基于食物的抗氧化剂似乎对治疗黄斑变性和白内障有用。补充维生素 A、维生素 C、维生素 E 和锌可能仅对高危人群预防年龄相关性黄斑变性有效。
