Calley Clifford S, Tillman Gail D, Womack Kyle, Moore Patricia, Hart John, Kraut Michael A
Berman Laboratory of Learning and Memory, Center for BrainHealth, The University of Texas at Dallas, Dallas, TX 75235, USA.
Cogn Behav Neurol. 2010 Sep;23(3):185-91. doi: 10.1097/WNN.0b013e3181c5e2d4.
Compare subjective reports of both memory and word-finding deficits to clinical diagnosis and objective neuropsychological testing.
With the increasing number of aging individuals with cognitive impairments, effective screening measures would improve the likelihood of detection. Subjective reports of symptoms are typically obtained in clinical settings, yet the validity of these reports is relatively unknown.
Clinical screening for dementia was carried out at an Alzheimer disease center. Dichotomous ratings for memory and word-finding/language problems were given by patients and neurologists. These ratings were compared with 13 neuropsychological measures of word-finding/language and episodic memory.
Ratings of memory by both patients and neurologists correlated well with standard neuropsychological measures of memory. However, both the patients' and physicians' ratings of word-finding/language impairments had notably less of a correlation with the relevant neuropsychological measures of word-finding/language.
Compared with ratings of memory, similar assessments of word-finding/language difficulties were relatively inaccurate, and thus poor predictors of impairment. It is imperative to develop effective screening methods that will help reveal cognitive impairments, as this issue will almost certainly become more pressing given the projected increase in the number of aging individuals and those with dementia.
将记忆和找词困难的主观报告与临床诊断及客观神经心理学测试进行比较。
随着认知障碍老年个体数量的增加，有效的筛查措施将提高检测的可能性。症状的主观报告通常在临床环境中获取，但其有效性相对未知。
在一个阿尔茨海默病中心进行痴呆的临床筛查。患者和神经科医生对记忆和找词/语言问题进行二分法评分。将这些评分与13项找词/语言和情景记忆的神经心理学指标进行比较。
患者和神经科医生对记忆的评分与记忆的标准神经心理学指标相关性良好。然而，患者和医生对找词/语言障碍的评分与找词/语言相关的神经心理学指标的相关性明显较低。
与记忆评分相比，对找词/语言困难的类似评估相对不准确，因此对障碍的预测性较差。开发有效的筛查方法以帮助发现认知障碍势在必行，因为鉴于预计老年个体和痴呆患者数量的增加，这个问题几乎肯定会变得更加紧迫。
