Department of Radiological Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.
Med Phys. 2010 Jul;37(7):3560-8. doi: 10.1118/1.3455285.
The extensive use of multislice computed tomography (MSCT) and the associated increase in patient dose calls for an accurate dose evaluation technique. Optically stimulated luminescence (OSL) dosimetry provides a potential solution to the arising concerns over patient dose. This study was intended to evaluate the feasibility and accuracy of OSL dosimeter systems in the diagnostic CT x-ray beam energy range.
MSCT dose profiles were measured by irradiating OSL strips placed inside the extended PMMA head and body phantoms at different scan conditions by varying kVp settings (100, 120, and 140 kVp) and collimated beam widths (5, 10, 20, and 40 mm). All scans in this study were performed using a GE Lightspeed VCT scanner in axial mode. The exposed strips were then read out using a custom-made OSL strip reader and corrected with field-specific conversion factors. Based on the corrected OSL dose profile, the CTDI(450-OSL) and CTDI(l00-OSL) were evaluated. CTDI(100-IC) was also obtained using a 100 mm long pencil ionization chamber for accuracy verification. CTDI(100-efficiency) can be further evaluated by calculating the ratio of CTDI(100-OSL) and CTDI(450-OSL), which was compared to results from previous studies as well.
The OSL detectors were found to have good sensitivity and dose response over a wide range of diagnostic CT x-ray beam energy viz. the primary beam and the scatter tail section of the dose profile. The differences between CTDI100 values obtained using the OSL strips and those obtained with 100 mm long pencil ionization chamber were < +/- 5% for all scan conditions, indicating good accuracy of the OSL system. It was also found that the CTDI(100-efficiency) did not significantly change as the beam width increased and tube voltage changed. The average CTDI(100-efficiency) at the center of the head and body phantoms were 72.6% and 56.2%, respectively. The corresponding values for the periphery of the head and body phantoms were 85.0% and 81.7%. These results agreed very well with previous results from the literature using other detection techniques or Monte Carlo simulations.
The LED-based OSL system can be an accurate alternative device for CT dose evaluations. CTDI100 measurement with the use of a 100 mm pencil ionization chamber substantially underestimates the CTDIinfinity value even with 5 mm collimated beam width. The established complete set of CTDI(100-efficiency) correction factors for various scan parameters allows for accurately estimating CTDIinfinity with the current use of pencil chamber and dose phantoms. Combined with the simple calibration, it gives this work great potential to be used not only in routine clinical quality assurance checks but also as a promising tool for patient organ dose assessment.
多层螺旋 CT(MSCT)的广泛应用及其带来的患者剂量增加,需要一种准确的剂量评估技术。光激励发光(OSL)剂量测定为解决患者剂量问题提供了一种潜在的解决方案。本研究旨在评估 OSL 剂量计系统在诊断 CT X 射线束能量范围内的可行性和准确性。
通过在不同的扫描条件下(kVp 设置为 100、120 和 140 kVp,准直器宽度为 5、10、20 和 40 mm),将 OSL 条放置在扩展的 PMMA 头部和身体体模内,测量 MSCT 剂量分布。本研究中的所有扫描均在轴向模式下使用 GE Lightspeed VCT 扫描仪进行。然后,使用定制的 OSL 条读取器读取暴露的条带,并使用特定于场的转换因子进行校正。基于校正后的 OSL 剂量分布,评估 CTDI(450-OSL)和 CTDI(100-OSL)。还使用 100mm 长的铅笔电离室获得 CTDI(100-IC)以进行准确性验证。通过计算 CTDI(100-OSL)与 CTDI(450-OSL)的比值,可以进一步评估 CTDI(100-效率),并与之前的研究结果进行比较。
发现 OSL 探测器在宽范围的诊断 CT X 射线束能量范围内具有良好的灵敏度和剂量响应,即主束和剂量分布的散射尾部。对于所有扫描条件,使用 OSL 条获得的 CTDI100 值与使用 100mm 长铅笔电离室获得的 CTDI100 值之间的差异<+/-5%,表明 OSL 系统具有良好的准确性。还发现,随着束宽的增加和管电压的变化,CTDI(100-效率)并没有显著变化。头部和身体体模中心的平均 CTDI(100-效率)分别为 72.6%和 56.2%。头部和身体体模外围的相应值分别为 85.0%和 81.7%。这些结果与之前使用其他检测技术或蒙特卡罗模拟的文献中的结果非常吻合。
基于 LED 的 OSL 系统可以成为 CT 剂量评估的准确替代设备。即使使用 5mm 准直器宽度,使用 100mm 铅笔电离室进行 CTDI100 测量也会大大低估 CTDIinfinity 值。对于各种扫描参数,建立完整的 CTDI(100-效率)校正因子集,可以准确估计 CTDIinfinity。结合简单的校准,这项工作具有很大的潜力,不仅可以用于常规临床质量保证检查,还可以作为患者器官剂量评估的有前途的工具。