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使用 OSL 剂量仪和 ATOM 人体模型获取 CT 器官剂量图的方法。

A method to acquire CT organ dose map using OSL dosimeters and ATOM anthropomorphic phantoms.

机构信息

Division of Diagnostic Imaging Physics and Webster Center for Advanced Research and Education in Radiation, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

出版信息

Med Phys. 2013 Aug;40(8):081918. doi: 10.1118/1.4816299.

Abstract

PURPOSE

To present the design and procedure of an experimental method for acquiring densely sampled organ dose map for CT applications, based on optically stimulated luminescence (OSL) dosimeters "nanoDots" and standard ATOM anthropomorphic phantoms; and to provide the results of applying the method--a dose data set with good statistics for the comparison with Monte Carlo simulation result in the future.

METHODS

A standard ATOM phantom has densely located holes (in 3×3 cm or 1.5×1.5 cm grids), which are too small (5 mm in diameter) to host many types of dosimeters, including the nanoDots. The authors modified the conventional way in which nanoDots are used, by removing the OSL disks from the holders before inserting them inside a standard ATOM phantom for dose measurements. The authors solved three technical difficulties introduced by this modification: (1) energy dependent dose calibration for raw OSL readings; (2) influence of the brief background exposure of OSL disks to dimmed room light; (3) correct pairing between the dose readings and measurement locations. The authors acquired 100 dose measurements at various positions in the phantom, which was scanned using a clinical chest protocol with both angular and z-axis tube current modulations.

RESULTS

Dose calibration was performed according to the beam qualities inside the phantom as determined from an established Monte Carlo model of the scanner. The influence of the brief exposure to dimmed room light was evaluated and deemed negligible. Pairing between the OSL readings and measurement locations was ensured by the experimental design. The organ doses measured for a routine adult chest scan protocol ranged from 9.4 to 18.8 mGy, depending on the composition, location, and surrounding anatomy of the organs. The dose distribution across different slices of the phantom strongly depended on the z-axis mA modulation. In the same slice, doses to the soft tissues other than the spinal cord demonstrated relatively small variations, with the maximum COV around 11.4%. This might be attributed to the angular mA modulation, the placement of the dosimeters, the chest cavity of the scanned region, and the size of the phantom. Doses to the spinal cord were consistently lower than those to other soft tissues.

CONCLUSIONS

The method is suited for acquiring densely sampled organ dose maps, and can be used for studying dose distributions relevant to subject size, organ location, and clinical CT protocols.

摘要

目的

提出一种基于光激励发光(OSL)剂量计“nanoDots”和标准 ATOM 人体模型,获取 CT 应用中密集采样器官剂量图的实验方法设计和步骤;并提供应用该方法的结果——一个具有良好统计学特性的剂量数据集,以便将来与蒙特卡罗模拟结果进行比较。

方法

标准 ATOM 体模上有密集排列的小孔(3×3cm 或 1.5×1.5cm 网格),这些孔太小(直径 5mm),无法容纳包括 nanoDots 在内的许多类型的剂量计。作者修改了传统的 nanoDots 使用方法,在将 OSL 盘插入标准 ATOM 体模进行剂量测量之前,先将其从支架上取下。作者解决了由该修改引入的三个技术难题:(1)对原始 OSL 读数进行能量相关剂量校准;(2)OSL 盘短暂暴露于昏暗的环境光下的影响;(3)剂量读数与测量位置之间的正确配对。作者在体模的不同位置进行了 100 次剂量测量,体模使用具有角度和 Z 轴管电流调制的临床胸部协议进行扫描。

结果

根据从扫描仪建立的蒙特卡罗模型确定的体模内光束质量进行剂量校准。评估了 OSL 盘短暂暴露于昏暗环境光的影响,认为可以忽略不计。通过实验设计确保了 OSL 读数与测量位置之间的配对。根据常规成人胸部扫描协议测量的器官剂量范围为 9.4 至 18.8mGy,具体取决于器官的组成、位置和周围解剖结构。体模不同切片之间的剂量分布强烈依赖于 Z 轴 mA 调制。在同一切片中,除脊髓外的软组织剂量显示出相对较小的变化,最大 COV 约为 11.4%。这可能归因于角度 mA 调制、剂量计的放置、扫描区域的胸腔以及体模的大小。脊髓的剂量始终低于其他软组织的剂量。

结论

该方法适用于获取密集采样的器官剂量图,并可用于研究与受检者体型、器官位置和临床 CT 协议相关的剂量分布。

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