Vishnumurthy Kodumuru, Makriyannis Alexandros
Center for Drug Discovery, 360 Huntington Avenue, 116 Mugar Hall, Boston, Massachusetts 02115-5000, USA.
J Comb Chem. 2010 Sep 13;12(5):664-9. doi: 10.1021/cc100068a.
Microwave-promoted novel and efficient one-step parallel synthesis of dibenzopyranones and heterocyclic analogues from bromo arylcarboxylates and o-hydroxyarylboronic acids via Suzuki-Miyaura cross coupling reaction is described. Spontaneous lactonization gave dibenzopyranones and heterocyclic analogues bearing electron-donating and -withdrawing groups on both aromatic rings in good to excellent yields.
描述了通过铃木-宫浦交叉偶联反应，由溴代芳基羧酸盐和邻羟基芳基硼酸经微波促进一步高效平行合成二苯并吡喃酮及其杂环类似物的方法。自发内酯化反应以良好至优异的产率得到了在两个芳环上带有供电子基和吸电子基的二苯并吡喃酮及其杂环类似物。
