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低果糖饮食治疗儿童肥胖症:一项初步研究。

A low fructose diet in the treatment of pediatric obesity: a pilot study.

作者信息

Maier Ina B, Stricker Laura, Ozel Yelda, Wagnerberger Sabine, Bischoff Stephan C, Bergheim Ina

机构信息

Department of Nutritional Medicine (180 a), University of Hohenheim, Stuttgart, Germany.

出版信息

Pediatr Int. 2011 Jun;53(3):303-8. doi: 10.1111/j.1442-200X.2010.03248.x.

Abstract

BACKGROUND

Over the last three decades the prevalence of overweight and obesity has increased dramatically among children and adolescents worldwide. As the results of animal and human studies suggest that a diet rich in fructose may be a risk factor for the development of overweight, the aim of the pilot study was to evaluate if a dietary counseling aimed at a moderate reduction of dietary fructose intake (-50% in comparison to intake at baseline) has a positive effect on the body mass index (BMI) of overweight and obese children.

METHODS

Fifteen overweight or obese children aged 5-8 years were included into the 3 month dietary intervention study. At baseline and after 4 and 8 weeks children and their parents were trained to reduce fructose in the children's diet. Anthropometric parameters for calculating BMI and BMI standard deviation scores (BMI-SDS) as well as nutritional intake were assessed at baseline, after the 12-week intervention and after 12 week of follow up.

RESULTS

After the 12-week intervention children had significantly reduced their total energy, fructose, sucrose and glucose intake. BMI and BMI-SDS were significantly reduced by 0.68 kg/m(2) and 0.21, respectively, at the end of the intervention. At follow up, the BMI-SDS was significantly lower in comparison to baseline while the BMI was only decreased by trend (P= 0.08).

CONCLUSIONS

The results of our pilot study indicate that counseling aimed towards a moderate reduction of dietary fructose and/or general sugar intake may have a positive effect on BMI in overweight and obese children.

摘要

背景

在过去三十年中,全球儿童和青少年中超重和肥胖的患病率急剧上升。由于动物和人体研究结果表明,富含果糖的饮食可能是超重发展的一个风险因素,该初步研究的目的是评估旨在适度减少膳食果糖摄入量(与基线摄入量相比减少50%)的饮食咨询是否对超重和肥胖儿童的体重指数(BMI)有积极影响。

方法

15名5至8岁的超重或肥胖儿童被纳入为期3个月的饮食干预研究。在基线以及4周和8周后,对儿童及其父母进行培训,以减少儿童饮食中的果糖。在基线、12周干预后以及随访12周后,评估用于计算BMI和BMI标准差评分(BMI-SDS)的人体测量参数以及营养摄入量。

结果

经过12周的干预,儿童的总能量、果糖、蔗糖和葡萄糖摄入量显著减少。干预结束时,BMI和BMI-SDS分别显著降低了0.68kg/m²和0.21。在随访时,与基线相比,BMI-SDS显著降低,而BMI仅呈下降趋势(P = 0.08)。

结论

我们初步研究的结果表明,旨在适度减少膳食果糖和/或总糖摄入量的咨询可能对超重和肥胖儿童的BMI有积极影响。

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